Evidence map›Paper›PMID 35422623›Full record

ArticleNeuropsychiatric disease and treatment2022

Relationship Between Employment Status and Unstable Periods in Outpatients with Bipolar Disorder: A Multicenter Treatment Survey for Bipolar Disorder in Psychiatric Outpatient Clinics (MUSUBI) Study.

Atsuko Ikenouchi, Yusuke Konno, Yoshihisa Fujino, Naoto Adachi, Yukihisa Kubota, Takaharu Azekawa, Hitoshi Ueda, Koji Edagawa, Eiichi Katsumoto, Eiichiro Goto and 8 more

Abstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Work impairment in bipolar disorder compared to the healthy population: a systematic review.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Atsuko IkenouchiDepartment of Psychiatry, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.ORCID 0000-0001-8328-4608
Yusuke KonnoDepartment of Psychiatry, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.ORCID 0000-0001-7262-6916
Yoshihisa FujinoDepartment of Environmental Epidemiology, Institute of Ecological Sciences, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.ORCID 0000-0002-9126-206X
Naoto AdachiThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.ORCID 0000-0001-8376-4900
Yukihisa KubotaThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.ORCID 0000-0002-9837-6799
Takaharu AzekawaThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.ORCID 0000-0003-4294-4600
Hitoshi UedaThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Koji EdagawaThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Eiichi KatsumotoThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Eiichiro GotoThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Seiji HongoThe Japanese Association of Neuro-Psychiatric Clinics, Tokyo, Japan.
Masaki KatoThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.
Takashi TsuboiThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0002-8253-8888
Norio Yasui-FurukoriThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0002-4414-3770
Atsuo NakagawaThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0002-2294-2571
Toshiaki KikuchiThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.
Koichiro WatanabeThe Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.ORCID 0000-0002-0736-7070
Reiji YoshimuraDepartment of Psychiatry, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To clarify the relationship between the length of unstable periods and employment status of patients with bipolar disorder. Patients and Methods: Medical records of outpatients with bipolar disorder who visited 176 member clinics of the Japanese Association of Neuro-Psychiatric Clinics were investigated during September-October 2016, and details of their medical care and employment were surveyed using a questionnaire. The odds ratios (ORs) of length of unstable period and unemployment were analyzed with a logistic regression model. Results: The study included 816 patients, of whom 707 were employed full-time (continuous employment) and 70 were unemployed (loss of employment). Univariate analysis showed that ORs were statistically significant for patients who were unstable for "almost all" of the year (OR = 10.4 [4.48-24.28] p < 0.001), but not for "few" unstable periods (OR = 1.06 [0.56-1.98] p = 0.849) and for "significant" unstable periods (OR = 1.65 [0.73-3.74] p = 0.231) were not significantly different. Multivariate analysis showed that ORs were statistically "significant" for patients who were unstable for "almost all" (OR = 12.1 [4.37-33.3] p < 0.001), but not for "few" unstable periods (OR = 1.07 [0.55-2.07] p = 0.846) and for "significant" unstable periods (OR = 1.62 [0.66-3.98] p = 0.290) did not differ significantly. Conclusion: Patients with bipolar disorder with a long unstable period were associated with a higher risk of unemployment.

Indexed as

loss of employmentmood disordernationwide studyreal world

Identifiers

PMID35422623
PMCPMC9005072

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.