ArticleSynthesis2021
Condensation-Based Methods for the C-H Bond Functionalization of Amines.
Article in Synthesis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Deciphering competing reaction pathways in the α-C-H functionalization of unprotected alicyclic aminesOrganic chemistry frontiers : an international journal of organic chemistry · 2026Article
- Fluoride-activated silicon catalysis enables C(spChemical science · 2026Article
- Acridine/Lewis acid photocatalysis enables α-amidyl radical cyclizations.Organic chemistry frontiers : an international journal of organic chemistry · 2026Article
- Bimetallic MChemistryOpen · 2026Article
- A Divergent Asymmetric Total Synthesis of Coprophilin and Four Trichodermic Acids via a [1,5]-Hydride Shift-Aldol Cascade.Journal of the American Chemical Society · 2026Article
- SelectiveThe Journal of organic chemistry · 2025Article
- Acridine/Lewis Acid Complexes as Powerful Photocatalysts: A Combined Experimental and Mechanistic Study.ACS catalysis · 2024Article
- Photocatalytic Decarboxylative Alkylation of Cyclic Imine-BFJournal of the American Chemical Society · 2024Article
- Regioselective α-Phosphonylation of Unprotected Alicyclic Amines.Organic letters · 2024Article
- Redox-neutral α-functionalization of pyrrolidines: facile access to α-aryl-substituted pyrrolidines.RSC advances · 2024Article
- Alicyclic-Amine-Derived Imine-BFAngewandte Chemie (International ed. in English) · 2024Article
- Article
- Acid-Promoted Redox-Annulation toward 1,2-Disubstituted-5,6-dihydropyrrolo[2,1-α]isoquinolines: Synthesis of the Lamellarin Core.ACS omega · 2022Article
- Regioselective α-Cyanation of Unprotected Alicyclic Amines.Organic letters · 2022Article
- Synthesis of Polycyclic Isoindolines via α-C-H/N-H Annulation of Alicyclic Amines.Organic letters · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
This review aims to provide a comprehensive overview of condensation-based methods for the C-H bond functionalization of amines that feature azomethine ylides as key intermediates. These transformations are typically redox-neutral and share common attributes with classic name reactions such as the Strecker, Mannich, Friedel-Crafts, Pictet-Spengler, and Kabachnik-Fields reaction, while incorporating a redox-isomerization step. This approach provides an ideal platform to rapidly transform simple starting materials into complex amines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.