ReviewNature reviews. Neuroscience2022
Networking brainstem and basal ganglia circuits for movement.
Review in Nature reviews. Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
115 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Neuropeptide S modulation of learning and memory: a systematic review.Behavioral and brain functions : BBF · 2026Pooled it
- Medical device-based neuromodulation for motor symptoms in Parkinson's disease: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Skin-attached bioadhesive patch enabling ultrasound deep brain stimulation and real-time electrophysiological monitoring for REM sleep enhancement.Nature communications · 2026Trial
- Surgery versus Botulinum Toxin A for Treatment of Post-Stroke Upper-Limb Spasticity: White Matter Changes, Function, and Quality-of-Life-A Randomized Controlled Trial.Neural plasticity · 2026Trial
- Roles of spinal V3 interneurons: Roles in controlling movement in healthy and injured conditions.Neural regeneration research · 2026Article
- Vestibular nucleus stimulation for ameliorating locomotor dynamics in a Parkinsonian mouse model.Nature communications · 2026Article
- Brain-Wide Activations Related to Forepaw Force Control Identified by Behaving Mouse FMRI.eNeuro · 2026Article
- Altered locus coeruleus functional connectivity in migraine without aura based on resting-state functional magnetic resonance imaging.Journal of oral & facial pain and headache · 2026Article
- Conserved role of primary motor cortex in the control of prehension in mice and macaques.Cell reports · 2026Article
- Motor cortex directly excites the substantia nigra pars reticulata, the basal ganglia output nucleus.Nature communications · 2026Article
- The parafascicular thalamus steers attention to facilitate learning.bioRxiv : the preprint server for biology · 2026Article
- Low-intensity transcranial ultrasound stimulation suppresses abnormal neural oscillations in the motor cortex by stimulating STN in α-synucleinActa neuropathologica communications · 2026Article
- Wearable Myoelectric Interface for Neurorehabilitation (MINT) to Recover Arm Activity After Stroke: A Randomized Controlled Trial.Neurorehabilitation and neural repair · 2026Article
- Beyond the Homunculus-SCAN-AMN as a Shared Action-Oriented Neural Substrate across Movement Disorders.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Poorer Physical Function Is Associated With Elevated Spatial Entropy in the Aging Brain Network Landscape.Aging cell · 2026Article
- Redefining the central pattern generator for vertebrate locomotion.Nature reviews. Neuroscience · 2026Review
- Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Basal ganglia output dynamically controls skilled forelimb kinematics in real time.bioRxiv : the preprint server for biology · 2026Article
- Glutamatergic projections from the substantia nigra pars reticulata to the dorsal raphe nucleus regulate male social hierarchies.PLoS biology · 2026Article
- Corticothalamic communication for action coordination in a skilled motor behavior.Nature neuroscience · 2026Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The execution and learning of diverse movements involve neuronal networks distributed throughout the nervous system. The brainstem and basal ganglia are key for processing motor information. Both harbour functionally specialized populations stratified on the basis of axonal projections, synaptic inputs and gene expression, revealing a correspondence between circuit anatomy and function at a high level of granularity. Neuronal populations within both structures form multistep processing chains dedicated to the execution of specific movements; however, the connectivity and communication between these two structures is only just beginning to be revealed. The brainstem and basal ganglia are also embedded into wider networks and into systems-level loops. Important networking components include broadcasting neurons in the cortex, cerebellar output neurons and midbrain dopaminergic neurons. Action-specific circuits can be enhanced, vetoed, work in synergy or competition with others, or undergo plasticity to allow adaptive behaviour. We propose that this highly specific organization of circuits in the motor system is a core ingredient for supporting behavioural specificity, and at the same time for providing an adequate substrate for behavioural flexibility.
Indexed as
Identifiers
35422525What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.