Evidence map›Paper›PMID 35422445›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

A Pipeline for Automated Voxel Dosimetry: Application in Patients with Multi-SPECT/CT Imaging After

Yuni K Dewaraja, David M Mirando, Avery B Peterson, Jeremy Niedbala, John D Millet, Justin K Mikell, Kirk A Frey, Ka Kit Wong, Scott J Wilderman, Aaron S Nelson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 32 citations in OpenAlex.

  1. High Quantitative Accuracy Is Possible withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  2. Dosimetry-Driven Personalization of Radiopharmaceutical Therapies: Evidence and Opportunities.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Review
  3. Article
  4. Swin UNETR-based prediction of [BMC medical imaging · 2026
    Article
  5. Article
  6. Inter-institutional variability in kidney dosimetry duringRadiological physics and technology · 2026
    Article
  7. Review
  8. Article
  9. Lesion Absorbed Dose-Response Relationship in Patients with Metastatic Castration-Resistant Prostate Cancer Undergoing [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  10. Article
  11. Case of the Season:Seminars in roentgenology · 2025
    Article
  12. CanJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  13. Multicycle Dosimetric Behavior and Dose-Effect Relationships in [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Success ofEndocrine oncology (Bristol, England) · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yuni K DewarajaDepartment of Radiology, University of Michigan, Ann Arbor, Michigan; yuni@umich.edu.
David M MirandoMIM Software Inc., Cleveland, Ohio.
Avery B PetersonDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Jeremy NiedbalaDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
John D MilletDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Justin K MikellRadiation Oncology, University of Michigan, Ann Arbor, Michigan.
Kirk A FreyDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Ka Kit WongDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Scott J WildermanDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Aaron S NelsonMIM Software Inc., Cleveland, Ohio.
University of Michigan · USWayne State University · US

Funding

Bringing Capacity for Theranostic Dosimetry Planning to the Nuclear Medicine ClinicR01CA240706 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DEWARAJA, YUNI K · 2020 to 2024
$3.0M
NCI NIH HHS R01 CA240706
6 · The paper itself

Abstract

Patient-specific dosimetry in radiopharmaceutical therapy (RPT) is impeded by the lack of tools that are accurate and practical for the clinic. Our aims were to construct and test an integrated voxel-level pipeline that automates key components (organ segmentation, registration, dose-rate estimation, and curve fitting) of the RPT dosimetry process and then to use it to report patient-specific dosimetry in

Indexed as

Neuroendocrine TumorsSingle Photon Emission Computed Tomography Computed TomographyHumansPositron-Emission TomographyRadioisotopesRadiometryRadionuclide ImagingRadiopharmaceuticalsReceptors, PeptideTomography, Emission-Computed, Single-Photoncopper dotatate CU-64RadioisotopesRadiopharmaceuticalsReceptors, Peptide177LudosimetryMonte Carloradionuclide therapySPECT/CTtheranostics

Identifiers

PMID35422445
PMCPMC9635679
OpenAlexW4224045983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.