Evidence map›Paper›PMID 35422444›Full record

Observational studyJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Konstantin Messerschmidt, Henryk Barthel, Matthias Brendel, Cordula Scherlach, Karl-Titus Hoffmann, Boris-Stephan Rauchmann, Michael Rullmann, Kenneth Marek, Victor L Villemagne, Jost-Julian Rumpf and 28 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Longitudinal monitoring of tau aggregation in progressive supranuclear palsy with [Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  7. Article
  8. Review
  9. A Biomarker-Based Classification of Corticobasal Syndrome.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  10. First-in-human PET neuroimaging of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  11. Developing a novel reference region for [European journal of nuclear medicine and molecular imaging · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
    Review
  17. Review
  18. Diagnosis and Management of Progressive Corticobasal Syndrome.Current treatment options in neurology · 2024
    Article
  19. Tau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies.European journal of nuclear medicine and molecular imaging · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 7 institutions in 2 countries.

Konstantin MesserschmidtDepartment of Nuclear Medicine, Leipzig University Medical Center, Leipzig, Germany; konstantin.messerschmidt@medizin.uni-leipzig.de.
Henryk BarthelDepartment of Nuclear Medicine, Leipzig University Medical Center, Leipzig, Germany.
Matthias BrendelDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich, Germany.
Cordula ScherlachDepartment of Neuroradiology, Leipzig University Medical Center, Leipzig, Germany.
Karl-Titus HoffmannDepartment of Neuroradiology, Leipzig University Medical Center, Leipzig, Germany.
Boris-Stephan RauchmannDepartment of Radiology, University Hospital of Munich, LMU Munich, Munich, Germany.
Michael RullmannDepartment of Nuclear Medicine, Leipzig University Medical Center, Leipzig, Germany.
Kenneth MarekInviCRO LLC, Boston, Massachusetts.
Victor L VillemagneDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jost-Julian RumpfDepartment of Neurology, Leipzig University Medical Center, Leipzig, Germany.
Dorothee SaurDepartment of Neurology, Leipzig University Medical Center, Leipzig, Germany.
Matthias L SchroeterClinic for Cognitive Neurology, Leipzig University Medical Center, Leipzig, Germany.
Andreas SchildanDepartment of Nuclear Medicine, Leipzig University Medical Center, Leipzig, Germany.
Marianne PattDepartment of Nuclear Medicine, Leipzig University Medical Center, Leipzig, Germany.
Leonie BeyerDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich, Germany.
Mengmeng SongDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich, Germany.
Carla PalleisDepartment of Neurology, University Hospital of Munich, LMU Munich, Munich, Germany.
Sabrina KatzdoblerDepartment of Neurology, University Hospital of Munich, LMU Munich, Munich, Germany.
Urban M FietzekDepartment of Neurology, University Hospital of Munich, LMU Munich, Munich, Germany.
Gesine RespondekDepartment of Neurology, Hannover Medical School, Hannover, Germany.
Maximilian ScheifeleDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich, Germany.
Alexander NitschmannDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich, Germany.
Christian ZachDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich, Germany.
Olivier BarretInviCRO LLC, Boston, Massachusetts.
Jennifer MadoniaInviCRO LLC, Boston, Massachusetts.
David RussellInviCRO LLC, Boston, Massachusetts.
Andrew W StephensLife Molecular Imaging GmbH, Berlin, Germany; and.
Norman KoglinLife Molecular Imaging GmbH, Berlin, Germany; and.
Sigrun RoeberCenter for Neuropathology and Prion Research, University Hospital of Munich, LMU Munich, Munich, Germany.
Jochen HermsCenter for Neuropathology and Prion Research, University Hospital of Munich, LMU Munich, Munich, Germany.
Kai BötzelDepartment of Neurology, University Hospital of Munich, LMU Munich, Munich, Germany.
Peter BartensteinDepartment of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich, Germany.
Johannes LevinGerman Center for Neurodegenerative Diseases, Site Munich, Bonn, Germany.
John P SeibylInviCRO LLC, Boston, Massachusetts.
Günter HöglingerGerman Center for Neurodegenerative Diseases, Site Munich, Bonn, Germany.
Joseph ClassenDepartment of Neurology, Leipzig University Medical Center, Leipzig, Germany.
Osama SabriDepartment of Nuclear Medicine, Leipzig University Medical Center, Leipzig, Germany.
German Imaging Initiative for Tauopathies (GII4T)
Leipzig University · DELMU Klinikum · DELudwig-Maximilians-Universität München · DEInvicro (United States) · USABT Molecular Imaging (United States) · USMedizinische Hochschule Hannover · DEUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive supranuclear palsy (PSP) is a 4-repeat tauopathy movement disorder that can be imaged by the

Indexed as

Supranuclear Palsy, ProgressiveAtrophyFluorine RadioisotopesHumansMagnetic Resonance ImagingPyridinestau Proteins((18)F)PI-2620Fluorine RadioisotopesPyridinestau Proteins18F-PI-26204R-tauopathymidbrain atrophyprogressive supranuclear palsytau PET

Identifiers

PMID35422444
PMCPMC9635682
OpenAlexW4224014734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.