Evidence map›Paper›PMID 35422437›Full record

ArticleLife science alliance2022

Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis.

Nina Tanaskovic, Mattia Dalsass, Marco Filipuzzi, Giorgia Ceccotti, Alessandro Verrecchia, Paola Nicoli, Mirko Doni, Daniela Olivero, Diego Pasini, Haruhiko Koseki and 3 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Nina TanaskovicEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.ORCID 0000-0001-7412-9139
Mattia DalsassEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.ORCID 0000-0003-1712-1071
Marco FilipuzziEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.
Giorgia CeccottiEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.
Alessandro VerrecchiaEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.ORCID 0000-0002-8596-6650
Paola NicoliEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.
Mirko DoniEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.ORCID 0000-0001-7099-2701
Daniela OliveroLaboratorio Analisi Veterinarie BiEsseA, A Company of Scil Animal Care Company Srl, Milan, Italy.ORCID 0000-0002-6667-7546
Diego PasiniEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.
Haruhiko KosekiLaboratory of Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID 0000-0001-8424-5854
Arianna SabòEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy.
Andrea BissoEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy bissoand81@gmail.com bruno.amati@ieo.it.ORCID 0000-0002-7158-8740
Bruno AmatiEuropean Institute of Oncology (IEO) - IRCCS, Milan, Italy bissoand81@gmail.com bruno.amati@ieo.it.ORCID 0000-0002-2958-1799
European Institute of Oncology · ITChiba University · JPUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Max is an obligate dimerization partner for the Myc transcription factors and for several repressors, such as Mnt, Mxd1-4, and Mga, collectively thought to antagonize Myc function in transcription and oncogenesis. Mga, in particular, is part of the variant Polycomb group repressive complex PRC1.6. Here, we show that ablation of the distinct PRC1.6 subunit Pcgf6-but not Mga-accelerates Myc-induced lymphomagenesis in Eµ-

Indexed as

CarcinogenesisPolycomb Repressive Complex 1AnimalsMicePolycomb-Group ProteinsProto-Oncogene Proteins c-mycMyc protein, mousePcgf6 protein, mousePolycomb-Group ProteinsPolycomb Repressive Complex 1Proto-Oncogene Proteins c-myc

Identifiers

PMID35422437
PMCPMC9012912
OpenAlexW4226095078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.