ArticleEuropean journal of clinical nutrition2022
Vitamin C status and its change in relation to glucose-lipid metabolism in overweight and obesity patients following laparoscopic sleeve gastrectomy.
Article in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Relationship Between Hypovitaminosis C, Obesity, and Features of Metabolic Syndrome-A Narrative Review.Nutrition reviews · 2026Review
- Serum vitamin C associated with lipids levels in children and adolescents: a national cross-sectional study.Nutrition & metabolism · 2025Article
- Article
- Association between serum vitamin C and body mass index in adolescents aged 12-19 years.BMC public health · 2024Article
- A Systematized Review of the Relationship Between Obesity and Vitamin C Requirements.Current developments in nutrition · 2024Review
- Effects of dietary vitamins on obesity-related metabolic parameters.Journal of nutritional science · 2023Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAimed to demonstrate the association of VC and metabolism in the obesity or overweight and determine VC changes after laparoscopic sleeve gastrectomy (LSG).
methodsA total of 253 overweight or people with obesity were recruited, including 61 with LSG. They were divided into group A (VC < 34 ug/ml) and group B (VC ≥ 34 ug/ml). Glucose-lipid metabolic parameters were compared, and VC status before and 6 and 12 months after LSG were measured.
results(1) Body weight, body mass index (BMI), neck circumference (NC), waist circumference (WC), hip circumference (HC), waist-to-hip ratio, heart rate (HR), diastolic systolic pressure (DBP), 2-hour postprandial glucose (2h-BG), fasting insulin (FINS), 2-hour postprandial insulin (2h-INS), glycosylated hemoglobin (HBG), homeostasis model of insulin resistance (HOMA-IR), total cholesterol (TCH), triglyceride (TG) and free fatty acid (FFA) were higher while high-density lipoprotein (HDL-C) was lower in group A than group B (p < 0.05). (2) VC was negatively correlated with body weight, BMI, NC, WC and HC, HR, SBP, DBP, and 2h-BG, FINS, 2h-INS, HGB, HOMA-IR, TG and FFA, while positively with HDL-C (p < 0.05). (3) Patients with obesity or hypertriglyceridemia or low HDL-C had lower VC than corresponding group. (p < 0.05). (4) Logistic regression analysis showed that VC was the independent risk factor of hypertriglyceridemia, obesity and low HDL-C 5) VC concentrations were slightly increased in 6 months after LSG, and unchanged in 12 months after LSG.
conclusionVC was closely associated with glucose-lipid metabolism, and may play a protective role in metabolic disorders. LSG would not worsen the VC status or deficiency.
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