Evidence map›Paper›PMID 35422037›Full record

Observational studyRespiratory research2022

Rapidly improving acute respiratory distress syndrome in COVID-19: a multi-centre observational study.

Evdokia Gavrielatou, Katerina Vaporidi, Vasiliki Tsolaki, Nikos Tserlikakis, George E Zakynthinos, Eleni Papoutsi, Aikaterini Maragkuti, Athina G Mantelou, Dimitrios Karayiannis, Zafeiria Mastora and 7 more

Open access · goldAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Respiratory research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Evdokia GavrielatouFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Katerina VaporidiDepartment of Intensive Care Medicine, University Hospital of Heraklion, Medical School University of Crete, Heraklion, Greece.
Vasiliki TsolakiCritical Care Department, Faculty of Medicine, University Hospital of Larissa, University of Thessaly, Larissa, Greece.
Nikos TserlikakisDepartment of Intensive Care Medicine, University Hospital of Heraklion, Medical School University of Crete, Heraklion, Greece.
George E ZakynthinosCritical Care Department, Faculty of Medicine, University Hospital of Larissa, University of Thessaly, Larissa, Greece.
Eleni PapoutsiFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Aikaterini MaragkutiFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Athina G MantelouFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Dimitrios KarayiannisFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Zafeiria MastoraFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Dimitris GeorgopoulosDepartment of Intensive Care Medicine, University Hospital of Heraklion, Medical School University of Crete, Heraklion, Greece.
Epaminondas ZakynthinosCritical Care Department, Faculty of Medicine, University Hospital of Larissa, University of Thessaly, Larissa, Greece.
Christina RoutsiFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Spyros G ZakynthinosFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Edward J SchenckDivision of Pulmonary and Critical Care Medicine, Department of Medicine, New York-Presbyterian Hospital-Weill Cornell Medical Center, Weill Cornell Medicine, New York, NY, USA.
Anastasia KotanidouFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece.
Ilias I SiemposFirst Department of Critical Care Medicine and Pulmonary Services, Evangelismos Hospital, National and Kapodistrian University of Athens Medical School, 45-47 Ipsilantou Street, 10676, Athens, Greece. ils2007@med.cornell.edu.ORCID http://orcid.org/0000-0003-0036-3322
National and Kapodistrian University of Athens · GRUniversity of Crete · GRUniversity of Thessaly · GRNewYork–Presbyterian Hospital · US

Funding

Necroinflammatory Cell Death in SepsisK23HL151876 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHENCK, EDWARD JAMES · 2021 to 2025
$975k
Hellenic Foundation for Research and Innovation 80-1/15.10.2020Hellenic Thoracic Society (GR) 2019NHLBI NIH HHS K23 HL151876
6 · The paper itself

Abstract

backgroundBefore the pandemic of coronavirus disease (COVID-19), rapidly improving acute respiratory distress syndrome (ARDS), mostly defined by early extubation, had been recognized as an increasingly prevalent subphenotype (making up 15-24% of all ARDS cases), associated with good prognosis (10% mortality in ARDSNet trials). We attempted to determine the prevalence and prognosis of rapidly improving ARDS and of persistent severe ARDS related to COVID-19.

methodsWe included consecutive patients with COVID-19 receiving invasive mechanical ventilation in three intensive care units (ICU) during the second pandemic wave in Greece. We defined rapidly improving ARDS as extubation or a partial pressure of arterial oxygen to fraction of inspired oxygen ratio (PaO

resultsA total of 280 intubated patients met criteria of ARDS with a median PaO

conclusionsRapidly improving ARDS was not prevalent and was not associated with good prognosis among patients with COVID-19. This is starkly different from what has been previously reported for patients with ARDS not related to COVID-19. Our results on both rapidly improving ARDS and persistent severe ARDS may contribute to our understanding of trajectory of ARDS and its association with prognosis in patients with COVID-19.

Indexed as

COVID-19Respiratory Distress SyndromeHumansIntensive Care UnitsOxygenRespiration, ArtificialOxygenAcute respiratory distress syndromeAcute respiratory failureCoronavirusPneumoniaTrajectory

Identifiers

PMID35422037
PMCPMC9008400
OpenAlexW4223924053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.