Evidence map›Paper›PMID 35422008›Full record

ArticleClinical hypertension2022

Association of adherence measured by self-reported pill count with achieved blood pressure level in hypertension patients: a cross-sectional study.

Iin Ernawati, Eziah Ika Lubada, Ria Lusiyani, Rahmad Aji Prasetya

Open access · diamondAbstract read
In one paragraph

Article in Clinical hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Iin ErnawatiDepartment of Clinical and Community Pharmacy, Akademi Farmasi Surabaya, Surabaya, East Java, Indonesia. iinernawati.apt@gmail.com.
Eziah Ika LubadaDepartment of Clinical and Community Pharmacy, Akademi Farmasi Surabaya, Surabaya, East Java, Indonesia.
Ria LusiyaniDepartment of Clinical and Community Pharmacy, Akademi Farmasi Surabaya, Surabaya, East Java, Indonesia.
Rahmad Aji PrasetyaDepartment of Clinical and Community Pharmacy, Akademi Farmasi Surabaya, Surabaya, East Java, Indonesia.
University of Surabaya · ID

Funding

Internal research fund of Akademi Farmasi Surabaya 080/AKFAR-SBY/SK.01.8/2020
6 · The paper itself

Abstract

backgroundMedication adherence plays an essential role in controlling blood pressure to reduce morbidity and mortality of hypertension disease. Thus, this study aimed to determine the association of medication adherence measured by self-reported pill count with blood pressure levels among patients at several community health centers in Surabaya.

methodsAdherence was assessed using the pill count method by comparing the total number of antihypertension drugs taken with the prescribed drugs. The inclusion criteria involved hypertensive patients who received antihypertension drugs, specifically adults and elderly, except the pregnant woman. The patient blood pressure was measured by healthcare workers in the targeted community health centers. Descriptive and multivariable logistic regression analyses were performed to assess factors associated with medication adherence with blood pressure levels.

resultsA total of 264 hypertensive outpatients participating in this study, 77.65% of participants were adherent to antihypertensive drugs based on the pill count method, and 40.91% of participants had controlled blood pressure. Patients with uncontrolled blood pressure were about six times (adjusted odds ratio [AOR]: 6.15; 95% confidence interval [CI]: 2.694-14.039; P = 0.000) more likely to have non-adherent medication than patients with controlled blood pressure. Reciprocally, non-adherent participants (pill count < 80%) were about six times (AOR: 6.081; 95% CI: 2.672-13.838; P = 0.000) more likely to have uncontrolled blood pressure compared to adherent patients (pill count ≥ 80%). Age less than 40 years old (AOR: 5.814; 95% CI: 1.519-22.252; P = 0.01) and having middle school educational level (AOR: 0.387; 95% CI: 0.153-0.974; P = 0.045) were found to be independent factors associated with uncontrolled blood pressure.

conclusionsThe result showed that non-adherence to antihypertension drugs is associated with uncontrolled blood pressure. Then, age could be associated with uncontrolled blood pressure. Thus, pharmacists and other healthcare providers should pay attention to improving medication adherence and maintaining the controlled blood pressure.

Indexed as

Antihypertensive drugBlood pressureHypertensionMedication adherencePill count

Identifiers

PMID35422008
PMCPMC9011980
OpenAlexW4223924603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.