Evidence map›Paper›PMID 35421911›Full record

ArticleAsian spine journal2022

The Prevalence of Coexisting Lumbar Spondylosis and Knee Osteoarthritis: A Systematic Review and Meta-Analysis.

Brjan Kaiji Betzler, Faye Yu Ci Ng, Yilun Huang, Bin Abd Razak Hr

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Asian spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07482527 (Thoracic Mobility Versus Hip Mobility Exercises to Core Stabilization in Lumbar Spondylitis), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07482527 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Thoracic Mobility Versus Hip Mobility Exercises to Core Stabilization in Lumbar Spondylitis

TypeinterventionalSponsorCairo UniversityRan2026 to 2026Enrolled60ConditionsIndividuals With Lumbar SpondylosisArmsGroup A : Core stabilization exercises (control group), Group B: Thoracic Mobility Exercises (1st experimental group only), Group C: Hip Mobility Exercises (2nd experimental group only)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Brjan Kaiji BetzlerLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Faye Yu Ci NgYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Yilun HuangDepartment of Orthopaedic Surgery, Sengkang General Hospital, Singapore.
Bin Abd Razak HrDepartment of Orthopaedic Surgery, Sengkang General Hospital, Singapore.
Nanyang Technological University · SGNational University of Singapore · SGSengkang General Hospital · SGSingHealth Duke-NUS Academic Medical Centre · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designA systematic review. PURPOSE: This study aimed to evaluate the prevalence of coexisting lumbar spondylosis (LS) and knee osteoarthritis (KOA), which has clinical implications on the screening, diagnosis, and management of orthopedic patients. OVERVIEW OF LITERATURE: Due to current global health trends, the number of affected patients is expected to increase substantially. However, no prior systematic reviews have discussed this topic.

methodsA systematic literature search was conducted in June 2021 in the PubMed, Embase, Scopus, CINAHL, and Cochrane CENTRAL databases. Clinical and epidemiological studies that reported quantitative data on the prevalence of coexisting LS and KOA were included. Studies which reported data on only LS or KOA alone were excluded. Odds ratios (ORs) and 95% confidence intervals (CI) for LS or KOA were retrieved or calculated for meta-analysis. Fixed-effects and random-effects models were used, and statistical significance was considered when p<0.05. Heterogeneity was evaluated using Cochran's Q test and the I2 statistic. Risk of bias was assessed using the MINORs (methodological index for nonrandomized studies) criteria.

resultsThis review included nine studies (5,758 patients). Four studies (4,164 patients) defined KOA and LS by a Kellgren-Lawrence (KL) grade of ≥2 and were included in the meta-analysis. Two other studies defined KOA and LS by a joint space narrowing grade of ≥2. The remaining three studies reported other outcomes. The combined ORs of having KOA of KL grade ≥2 due to LS was 1.75 (95% CI, 1.22-2.50; p=0.002), while the combined OR of having LS of KL grade ≥2 due to KOA was 1.84 (95% CI, 1.23-2.77; p=0.003).

conclusionsIn patients with either KOA or LS, the odds of having a concurrent knee-spine presentation are significantly increased. This may have implications for clinical decision-making and treatment strategies. Further high-level studies with larger patient populations are required to confirm these results in specific populations.

Indexed as

EpidemiologyKnee osteoarthritisPrevalenceSpondylosis

Identifiers

PMID35421911
PMCPMC9827201
OpenAlexW4223897514

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.