ArticleBrain stimulation
Simultaneous stereo-EEG and high-density scalp EEG recordings to study the effects of intracerebral stimulation parameters.
Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Methodologies to detect cortico-cortical evoked potentials: a systematic review.Frontiers in human neuroscience · 2025Pooled it
- Targeting intracranial electrical stimulation to network regions defined within individuals causes network-level effects.Journal of neurophysiology · 2026Article
- A geometry aware framework enhances noninvasive mapping of whole human brain dynamics.Nature biomedical engineering · 2026Article
- Depth-to-scalp spatiotemporal dynamics for stereo-EEG.Epilepsy & behavior reports · 2025Article
- The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Scalp EEG predicts intracranial brain activity in humans.bioRxiv : the preprint server for biology · 2025Article
- Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks.Nature communications · 2025Article
- Prefrontal Oscillatory Slowing in Early-Course Schizophrenia Is Associated With Worse Cognitive Performance and Negative Symptoms: A Transcranial Magnetic Stimulation-Electroencephalography Study.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- [Applications and prospects of electroencephalography technology in neurorehabilitation assessment and treatment].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Review
- XDL-ESI: Electrophysiological Sources Imaging via explainable deep learning framework with validation on simultaneous EEG and iEEG.NeuroImage · 2024Article
- A Method for the Spatial Interpolation of EEG Signals Based on the Bidirectional Long Short-Term Memory Network.Sensors (Basel, Switzerland) · 2024Article
- Simultaneous invasive and non-invasive recordings in humans: A novel Rosetta stone for deciphering brain activity.Journal of neuroscience methods · 2024Review
- CARLA: Adjusted common average referencing for cortico-cortical evoked potential data.Journal of neuroscience methods · 2024Article
- The Neurostimulationist will see you now: prescribing direct electrical stimulation therapies for the human brain in epilepsy and beyond.Frontiers in human neuroscience · 2024Review
- Single-pulse electrical stimulation artifact removal using the novel matching pursuit-based artifact reconstruction and removal method (MPARRM).Journal of neural engineering · 2023Article
- Reliability and Validity of Transcranial Magnetic Stimulation-Electroencephalography Biomarkers.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Review
- Natural Oscillatory Frequency Slowing in the Premotor Cortex of Early-Course Schizophrenia Patients: A TMS-EEG Study.Brain sciences · 2023Article
- Experimental suppression of transcranial magnetic stimulation-electroencephalography sensory potentials.Human brain mapping · 2022Article
- Magnetoencephalography can reveal deep brain network activities linked to memory processes.Human brain mapping · 2022Article
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Authors and funding
17 authors at 9 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCortico-cortical evoked potentials (CCEPs) recorded by stereo-electroencephalography (SEEG) are a valuable tool to investigate brain reactivity and effective connectivity. However, invasive recordings are spatially sparse since they depend on clinical needs. This sparsity hampers systematic comparisons across-subjects, the detection of the whole-brain effects of intracortical stimulation, as well as their relationships to the EEG responses evoked by non-invasive stimuli.
objectiveTo demonstrate that CCEPs recorded by high-density electroencephalography (hd-EEG) provide additional information with respect SEEG alone and to provide an open, curated dataset to allow for further exploration of their potential.
methodsThe dataset encompasses SEEG and hd-EEG recordings simultaneously acquired during Single Pulse Electrical Stimulation (SPES) in drug-resistant epileptic patients (N = 36) in whom stimulations were delivered with different physical, geometrical, and topological parameters. Differences in CCEPs were assessed by amplitude, latency, and spectral measures.
resultsWhile invasively and non-invasively recorded CCEPs were generally correlated, differences in pulse duration, angle and stimulated cortical area were better captured by hd-EEG. Further, intracranial stimulation evoked site-specific hd-EEG responses that reproduced the spectral features of EEG responses to transcranial magnetic stimulation (TMS). Notably, SPES, albeit unperceived by subjects, elicited scalp responses that were up to one order of magnitude larger than the responses typically evoked by sensory stimulation in awake humans.
conclusionsCCEPs can be simultaneously recorded with SEEG and hd-EEG and the latter provides a reliable descriptor of the effects of SPES as well as a common reference to compare the whole-brain effects of intracortical stimulation to those of non-invasive transcranial or sensory stimulations in humans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.