Evidence map›Paper›PMID 35421343›Full record

ArticleCell host & microbe2022

Host-microbe circadian dynamics: Finding a rhythm and hitting a groove in scientific inquiry.

Katya Frazier, Vanessa A Leone

Abstract read
In one paragraph

Article in Cell host & microbe, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Bacterial growth dynamics in a rhythmic symbiosis.Molecular biology of the cell · 2024
    Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Katya FrazierDepartment of Medicine, University of Chicago, Chicago, IL 60637, USA.
Vanessa A LeoneDepartment of Animal & Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: valeone@wisc.edu.

Funding

Diurnal Oscillations in Gut Microbes and Host Immunity in Health and ObesityK01DK111785 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LEONE, VANESSA ANNE · 2017 to 2021
$723k
The role of the peripheral liver circadian clock and diurnal gut microbial mediators in the regulation of hepatic gluconeogenesisF31DK122714 · NIDDK · UNIVERSITY OF CHICAGO · PI FRAZIER, KATYA MORGAN · 2019 to 2021
$137k
NIDDK NIH HHS F31 DK122714NIDDK NIH HHS K01 DK111785
6 · The paper itself

Abstract

Gut microbes are mediators of organismal-level circadian rhythms, responding to and transducing environmental cues. Gut microbes also exhibit rhythms, yet their contribution to a healthy microbiome remains unclear. We present our path to identifying host-microbe circadian dynamics related to health and outline a series of forward-thinking questions requiring further exploration.

Indexed as

Gastrointestinal MicrobiomeCircadian Rhythm

Identifiers

PMID35421343
PMCPMC9720840

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.