Evidence map›Paper›PMID 35421317›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022

A novel nonlinear analysis of blood flow dynamics applied to the human lung.

Richard B Buxton, G Kim Prisk, Susan R Hopkins

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Richard B BuxtonDepartment of Radiology, University of California San Diego, La Jolla, California.ORCID 0000-0002-8819-1256
G Kim PriskDepartment of Medicine, University of California San Diego, La Jolla, California.ORCID 0000-0002-6344-4720
Susan R HopkinsDepartment of Radiology, University of California San Diego, La Jolla, California.ORCID 0000-0002-8672-0986
University of California San Diego · US

Funding

Spatial-Temporal Dynamics of Blood Flow in the Normal Human LungR01HL104118 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BUXTON, RICHARD BRUCE, PRISK, GORDON KIM · 2011 to 2014
$2.5M
Imaging Hypoxic Pulmonary Vasoconstriction in the Aging Lung with Proton MRIR01HL129990 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOPKINS, SUSAN R · 2016 to 2019
$2.4M
Imaging Nonlinear Control of the Pulmonary Circulation with Proton MRIR21HL118539 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOPKINS, SUSAN R · 2013 to 2014
$411k
NHLBI NIH HHS R01 HL104118NHLBI NIH HHS R01 HL129990NHLBI NIH HHS R21 HL118539
6 · The paper itself

Abstract

The spatial/temporal dynamics of blood flow in the human lung can be measured noninvasively with magnetic resonance imaging (MRI) using arterial spin labeling (ASL). We report a novel data analysis method using nonlinear prediction to identify dynamic interactions between blood flow units (image voxels), potentially providing a probe of underlying vascular control mechanisms. The approach first estimates the linear relationship (predictability) of one voxel time series with another using correlation analysis, and after removing the linear component, it estimates the nonlinear relationship with a numerical mutual information approach. Dimensionless global metrics for linear prediction (

Indexed as

Altitude SicknessPulmonary EdemaAltitudeDisease SusceptibilityHumansHypertension, PulmonaryHypoxiaLungSpin LabelsSpin Labelsarterial spin labelinghigh-altitude pulmonary edemanonlinear analysisnonlinear dynamicspulmonary blood flow dynamics

Identifiers

PMID35421317
PMCPMC9190737
OpenAlexW4224086470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.