Evidence map›Paper›PMID 35421222›Full record

ArticlePhysical therapy2022

The SIT-PT Trial Protocol: A Dose-Matched Randomized Clinical Trial Comparing 2 Physical Therapist Interventions for Infants and Toddlers With Cerebral Palsy.

Stacey C Dusing, Regina T Harbourne, Lin-Ya Hsu, Natalie A Koziol, Kari Kretch, Barbara Sargent, Sandra Jensen-Willett, Sarah Westcott McCoy, Douglas L Vanderbilt

Registry-linked trialOpen access · bronzeAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Physical therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04230278 (Evaluation of the Efficacy of a Physical Therapy Intervention Targeting Sitting and Reaching for Young Children With Cerebral Palsy), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04230278 naactive not recruitingnot on this map

Evaluation of the Efficacy of a Physical Therapy Intervention Targeting Sitting and Reaching for Young Children With Cerebral Palsy

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2021 to 2026Enrolled98ConditionsCerebral PalsyArmsSTART-Play Physical Therapy, Usual Care Physical Therapy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Stacey C DusingOstrow School of Dentistry, Division of Physical Therapy and Biokinesiology, University of Southern California, Los Angeles, California, USA.ORCID 0000-0003-3847-3893
Regina T HarbourneRangos School of Health Sciences, Department of Physical Therapy, Duquesne University, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-8099-4145
Lin-Ya HsuDepartment of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA.
Natalie A KoziolCollege of Education and Human Sciences, Nebraska Center for Research on Children, Youth, Families and Schools, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Kari KretchOstrow School of Dentistry, Division of Physical Therapy and Biokinesiology, University of Southern California, Los Angeles, California, USA.
Barbara SargentOstrow School of Dentistry, Division of Physical Therapy and Biokinesiology, University of Southern California, Los Angeles, California, USA.
Sandra Jensen-WillettMunroe-Meyer Institute, Department of Physical Therapy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Sarah Westcott McCoyDepartment of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA.
Douglas L VanderbiltDevelopmental-Behavioral Pediatrics Section, Children's Hospital Los Angeles, USC Keck School of Medicine, Los Angeles, California, USA.
University of Southern California · USUniversity of Washington · USChildren's Hospital of Los Angeles · USDuquesne University · USNebraska Medical Center · USUniversity of Nebraska–Lincoln · US

Funding

Mentored Career DevelopmentKL2TR001854 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Elizabeth Rhea Erwin Burner, Amy Elizabeth West · 2016 to 2026
$9.0M
Evaluation of the Efficacy of a Physical Therapy Intervention Targeting Sitting and Reaching for Young Children with Cerebral PalsyR01HD101900 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DUSING, STACEY CHAPMAN, HARBOURNE, REGINA · 2020 to 2024
$3.0M
NCATS NIH HHS KL2 TR001854NICHD NIH HHS R01 HD101900
6 · The paper itself

Abstract

objectiveAlthough early intervention for infants at risk for cerebral palsy is routinely recommended, the content of intervention is poorly described, varies widely, and has mixed supporting evidence. The purpose of this study was to compare efficacy of 2 interventions grounded in differing domains of the International Classification of Functioning, Disability and Health on developmental outcomes of infants with or at high risk of cerebral palsy.

methodsInfants who meet inclusion criteria will be randomized into either Sitting Together and Reaching To Play or Movement, Orientation, Repetition, Exercise Physical Therapy groups. Both groups will receive intervention twice weekly for 3 months and follow-up at 3, 6, 9, and 12 months from baseline. The primary objectives compare changes over time and between groups in sitting, gross motor, and cognitive development. The setting is the infant's home unless the caregiver requests otherwise. One hundred and fifty infants between 8 and 24 months of age will be enrolled in 3 geographically, racially, and ethnically diverse sites: Los Angeles, California; Omaha, Nebraska; and Seattle, Washington. Enrolled infants will demonstrate motor delays, emerging sitting skills, and signs of neurologic impairment. Sitting Together and Reaching To Play targets activities including sitting, reaching, and motor-based problem solving to improve global development. In contrast, Movement, Orientation, Repetition, Exercise Physical Therapy focuses on strengthening and musculoskeletal alignment while encouraging repeated movement practice. Outcome measures include the Gross Motor Function Measure, Bayley Scales of Infant Development-IV, Assessment of Problem Solving in Play, and a Parent Child Interaction assessment. Enrolled children will maintain usual intervention services due to ethical concerns with intervention withdrawal. IMPACT: This will be the first study, to our knowledge, comparing efficacy of early physical therapy with dose-matched interventions and well-defined key principles. The outcomes will inform selection of key principle of intervention in this population.

Indexed as

Cerebral PalsyMotor Skills DisordersPhysical TherapistsChild, PreschoolEarly Intervention, EducationalHumansInfantPhysical Therapy ModalitiesRandomized Controlled Trials as TopicCognitive FunctionComparative Effectiveness ResearchInfantMotor DevelopmentPhysical Therapy TechniquesRehabilitation

Identifiers

PMID35421222
PMCPMC9291380
OpenAlexW4223918021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.