Evidence map›Paper›PMID 35421212›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2022

Nutritional Epigenetics in Cancer.

Maria J Barrero, Paloma Cejas, Henry W Long, Ana Ramirez de Molina

Abstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Clinical applications of abnormal DNA methylation in chronic myeloid leukemia.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria J BarreroMolecular Oncology Group, IMDEA Food, CEI UAM+CSIC, Madrid, Spain.ORCID 0000-0002-5990-7040
Paloma CejasDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Henry W LongDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Ana Ramirez de MolinaMolecular Oncology Group, IMDEA Food, CEI UAM+CSIC, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in the epigenome are well known to affect cancer development and progression. Epigenetics is highly influenced by the environment, including diet, which is a source of metabolic substrates that influence the synthesis of cofactors or substrates for chromatin and RNA modifying enzymes. In addition, plants are a common source of bioactives that can directly modify the activity of these enzymes. Here, we review and discuss the impact of diet on epigenetic mechanisms, including chromatin and RNA regulation, and its potential implications for cancer prevention and treatment.

Indexed as

HistonesNeoplasmsChromatinDNA MethylationEpigenesis, GeneticHumansRNAChromatinHistonesRNAbioactivesDNA methylationenhancerhistone modificationsmetabolismobesityRNA modifications

Identifiers

PMID35421212
PMCPMC9526851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.