Evidence map›Paper›PMID 35421188›Full record

ArticlePloS one2022

Genetic diversity of Cryptosporidium spp. in non-human primates in rural and urban areas of Ethiopia.

Ambachew W Hailu, Abraham Degarege, Beyene Petros, Damien Costa, Yonas Yimam Ayene, Ven-Ceslas Villier, Abdelmounaim Mouhajir, Loic Favennec, Romy Razakandrainibe, Haileeysus Adamu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Prevalence ofVeterinary world · 2024
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Ambachew W HailuDepartment of Microbial Cellular and Molecular Biology, Biomedical Sciences Stream Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0003-2958-5471
Abraham DegaregeDepartment of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.
Beyene PetrosDepartment of Microbial Cellular and Molecular Biology, Biomedical Sciences Stream Addis Ababa University, Addis Ababa, Ethiopia.
Damien CostaEA ESCAPE 7510, University of Medicine Pharmacy Rouen, Rouen, France.
Yonas Yimam AyeneDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Ven-Ceslas VillierEA ESCAPE 7510, University of Medicine Pharmacy Rouen, Rouen, France.
Abdelmounaim MouhajirEA ESCAPE 7510, University of Medicine Pharmacy Rouen, Rouen, France.
Loic FavennecEA ESCAPE 7510, University of Medicine Pharmacy Rouen, Rouen, France.
Romy RazakandrainibeEA ESCAPE 7510, University of Medicine Pharmacy Rouen, Rouen, France.
Haileeysus AdamuInstitute of Biotechnology, Addis 12 Ababa University, Addis Ababa, Ethiopia.
Addis Ababa University · ETSanté Publique France · FREpidémiosurveillance et circulation des parasites dans les environnements · FRTehran University of Medical Sciences · IRUniversity of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-Human Primates (NHPs) harbor Cryptosporidium genotypes that can infect humans and vice versa. NHPs Chlorocebus aethiops and Colobus guereza and humans have overlapping territories in some regions of Ethiopia, which may increase the risk of zoonotic transmission of Cryptosporidium. This cross-sectional study examined the molecular prevalence and subtypes of Cryptosporidium spp. from 185 fecal samples of Chlorocebus aethiops and Colobus guereza in rural and urban areas in Ethiopia. Samples were tested for Cryptosporidium infection using nested polymerase chain reaction (PCR), and subtypes were determined by sequencing a fragment of the 60-kDa glycoprotein gene (gp60). Of the 185 samples, fifty-one (27.56%) tested positive for Cryptosporidium infection. The species detected were C. parvum (n = 34), C. hominis (n = 12), and C. cuniculus (n = 3). Mixed infection with C. parvum and C. hominis were detected in 2 samples. Four C. hominis family subtypes (Ia, Ib, Id, and Ie) and one C. parvum family subtype (IIa) were identified. C. hominis IaA20 (n = 7) and C. parvum IIaA17G1R1 (n = 6) were the most prevalent subtypes detected. These results confirm that Chlorocebus aethiops and Colobus guereza can be infected with diverse C. parvum and C. hominis subtypes that can also potentially infect humans. Additional studies could help to understand the role of NHPs in the zoonotic transmission of Cryptosporidium in Ethiopia.

Indexed as

CryptosporidiosisCryptosporidiumAnimalsChlorocebus aethiopsColobusCross-Sectional StudiesEthiopiaFecesGenetic VariationGenotypePrimates

Identifiers

PMID35421188
PMCPMC9009656
OpenAlexW4224069575

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.