Evidence map›Paper›PMID 35421162›Full record

ArticlePloS one2022

Influence of advanced life support response time on out-of-hospital cardiac arrest patient outcomes in Taipei.

Hsuan-An Chen, Shuo-Ting Hsu, Ming-Ju Hsieh, Shyh-Shyong Sim, Sheng-En Chu, Wen-Shuo Yang, Yu-Chun Chien, Yao-Cheng Wang, Bin-Chou Lee, Edward Pei-Chuan Huang and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07695766 (Evaluation of CPR Training and Agonal Breathing Recognition Among New Taipei City Police Officers in Out-of-Hospital Cardiac Arrest Events), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07695766 nacompletednot on this mapstarted 2026, after this paper: background citation

Evaluation of CPR Training and Agonal Breathing Recognition Among New Taipei City Police Officers in Out-of-Hospital Cardiac Arrest Events

TypeinterventionalSponsorFar Eastern Memorial HospitalRan2026 to 2026Enrolled3,439ConditionsOut-of-hospital Cardiac Arrest (OHCA), Agonal Breathing, Cardiopulmonary Resuscitation TrainingArmsCPR Refresher and Agonal Breathing Recognition Training
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hsuan-An ChenDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.ORCID 0000-0003-0701-1944
Shuo-Ting HsuDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.ORCID 0000-0003-2753-0346
Ming-Ju HsiehDepartment of Emergency Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Shyh-Shyong SimDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Sheng-En ChuDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Wen-Shuo YangEmergency Medical Services Division, Taipei City Fire Department, Taipei City, Taiwan.
Yu-Chun ChienEmergency Medical Services Division, National Fire Agency, Ministry of the Interior, New Taipei City, Taiwan.
Yao-Cheng WangEmergency Medical Services Division, Taipei City Fire Department, Taipei City, Taiwan.
Bin-Chou LeeDepartment of Emergency Medicine, National Taiwan University Hospital, Taipei City Hospital, Zhongxiao Branch, Taipei, Taiwan.
Edward Pei-Chuan HuangDepartment of Emergency Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu City, Taiwan.
Hao-Yang LinDepartment of Emergency Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Matthew Huei-Ming MaDepartment of Emergency Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.ORCID 0000-0002-4388-9984
Wen-Chu ChiangDepartment of Emergency Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Jen-Tang SunDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.ORCID 0000-0003-2628-9917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association between out-of-hospital cardiac arrest patient survival and advanced life support response time remained controversial. We aimed to test the hypothesis that for adult, non-traumatic, out-of-hospital cardiac arrest patients, a shorter advanced life support response time is associated with a better chance of survival. We analyzed Utstein-based registry data on adult, non-traumatic, out-of-hospital cardiac arrest patients in Taipei from 2011 to 2015.

methodsPatients without complete data, witnessed by emergency medical technicians, or with response times of ≥ 15 minutes, were excluded. We used logistic regression with an exposure of advanced life support response time. Primary and secondary outcomes were survival to hospital discharge and favorable neurological outcomes (cerebral performance category ≤ 2), respectively. Subgroup analyses were based on presenting rhythms of out-of-hospital cardiac arrest, bystander cardiopulmonary resuscitation, and witness status.

resultsA total of 4,278 cases were included in the final analysis. The median advanced life support response time was 9 minutes. For every minute delayed in advanced life support response time, the chance of survival to hospital discharge would reduce by 7% and chance of favorable neurological outcome by 9%. Subgroup analysis showed that a longer advanced life support response time was negatively associated with the chance of survival to hospital discharge among out-of-hospital cardiac arrest patients with shockable rhythm and pulse electrical activity groups.

conclusionsIn non-traumatic, adult, out-of-hospital cardiac arrest patients in Taipei, a longer advanced life support response time was associated with declining odds of survival to hospital discharge and favorable neurologic outcomes, especially in patients presenting with shockable rhythm and pulse electrical activity.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesOut-of-Hospital Cardiac ArrestAdultElectric CountershockHumansReaction TimeRegistries

Identifiers

PMID35421162
PMCPMC9009650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.