ArticlePLoS biology2022
Biosecurity in an age of open science.
Article in PLoS biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Enhanced classification and identification of bacterial and viral microorganisms by integration of MALDI-TOF mass spectrometry with artificial intelligence.Scientific reports · 2026Article
- Methods for safely sharing dual-use genetic data.Frontiers in microbiology · 2026Article
- How will we prepare for an uncertain future? The value of open data and code for unborn generations facing climate change.Proceedings. Biological sciences · 2025Article
- Feasibility of ending tuberculosis in Shangrao City through active intervention measures: a mathematical study.Frontiers in public health · 2025Article
- Mapping variation in dual use risk assessments of synthetic biology projects.Frontiers in bioengineering and biotechnology · 2025Article
- Limiting open science? Three approaches to bottom-up governance of dual-use research of concern.Pathogens and global health · 2024Review
- Establishing a national biosafety and biosecurity agency for the United States.Frontiers in bioengineering and biotechnology · 2024Article
- Grand challenge in biosafety and biosecurity.Frontiers in bioengineering and biotechnology · 2024Article
- The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2024Article
- Article
- Must-have Qualities of Clinical Research on Artificial Intelligence and Machine LearningBalkan medical journal · 2023Review
- The use and acceptability of preprints in health and social care settings: A scoping review.PloS one · 2023Article
- The Need for Biosecurity Education in Biotechnology Curricula.Biodesign research · 2023Article
- Anthrax revisited: how assessing the unpredictable can improve biosecurity.Frontiers in bioengineering and biotechnology · 2023Article
- A guide to open science practices for animal research.PLoS biology · 2022Article
- The context matrix: Navigating biological complexity for advanced biodesign.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The risk of accidental or deliberate misuse of biological research is increasing as biotechnology advances. As open science becomes widespread, we must consider its impact on those risks and develop solutions that ensure security while facilitating scientific progress. Here, we examine the interaction between open science practices and biosecurity and biosafety to identify risks and opportunities for risk mitigation. Increasing the availability of computational tools, datasets, and protocols could increase risks from research with misuse potential. For instance, in the context of viral engineering, open code, data, and materials may increase the risk of release of enhanced pathogens. For this dangerous subset of research, both open science and biosecurity goals may be achieved by using access-controlled repositories or application programming interfaces. While preprints accelerate dissemination of findings, their increased use could challenge strategies for risk mitigation at the publication stage. This highlights the importance of oversight earlier in the research lifecycle. Preregistration of research, a practice promoted by the open science community, provides an opportunity for achieving biosecurity risk assessment at the conception of research. Open science and biosecurity experts have an important role to play in enabling responsible research with maximal societal benefit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.