Evidence map›Paper›PMID 35420910›Full record

ReviewCirculation research2022

Advances in Recurrent Stroke Prevention: Focus on Antithrombotic Therapies.

Brian Mac Grory, Shadi Yaghi, Charlotte Cordonnier, Luciano A Sposato, Jose G Romano, Seemant Chaturvedi

Abstract readReview
In one paragraph

Review in Circulation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian Mac GroryDepartment of Neurology, Duke University, Durham, NC (B.M.G.).ORCID 0000-0003-3914-8419
Shadi YaghiDepartment of Neurology, Brown University, Providence, RI (S.Y.).ORCID 0000-0003-0031-1004
Charlotte CordonnierUniv. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience and Cognition, F-59000 Lille, France (C.C.).ORCID 0000-0002-5697-6892
Luciano A SposatoDepartment of Neurology, Western University (L.A.S.).ORCID 0000-0001-6425-9343
Jose G RomanoDepartment of Neurology, University of Miami, Miami, FL (J.G.R.).ORCID 0000-0003-3667-2792
Seemant ChaturvediDepartment of Neurology, University of Maryland, Baltimore, MD (S.C.).ORCID 0000-0001-8660-7644

Funding

Mechanisms of Early Recurrence in Intracranial Atherosclerotic DiseaseR01NS084288 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LIEBESKIND, DAVID SIGMUND, PRABHAKARAN, SHYAM · 2014 to 2018
$3.0M
NINDS NIH HHS R01 NS084288
6 · The paper itself

Abstract

The past decade has seen significant advances in stroke prevention. These advances include new antithrombotic agents, new options for dyslipidemia treatment, and novel techniques for surgical stroke prevention. In addition, there is greater recognition of the benefits of multifaceted interventions, including the role of physical activity and dietary modification. Despite these advances, the aging of the population and the high prevalence of key vascular risk factors pose challenges to reducing the burden of stroke. Using a cause-based framework, current approaches to prevention of cardioembolic, cryptogenic, atherosclerotic, and small vessel disease stroke are outlined in this paper. Special emphasis is given to recent trials of antithrombotic agents, including studies that have tested combination treatments and responses according to genetic factors.

Indexed as

Fibrinolytic AgentsStrokeHumansRecurrenceRisk FactorsSecondary PreventionFibrinolytic Agentsatrial fibrillationendarterectomy, carotidforamen ovale, patentrandomized controlled trialstroke

Identifiers

PMID35420910
PMCPMC9015232

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.