ReviewProgress in biomaterials2022
Injectable hydrogels for bone and cartilage tissue engineering: a review.
Review in Progress in biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Hierarchical periosteum-bone composite scaffold with staged release of dexamethasone and endothelial cell derivatives for efficient critical-sized bone defect repair.Materials today. Bio · 2026Article
- Injectable hydrogels for bone regeneration: mechanical reinforcement strategies using nanoparticles and nanofibers.ADMET & DMPK · 2026Review
- Smart Polymer-Derived Injectable Hydrogels: Current Status and Future Perspectives.ACS polymers Au · 2025Review
- From molecular regulation to tissue repair: hydrogels in the fight against intervertebral disc degeneration.Annals of medicine · 2025Review
- Catalyst Selection for Body-Temperature Curable Polyurethane Networks from Poly(δ-Decalactone) and Lysine Diisocyanate.Polymers · 2025Article
- Bioinspired injectable hydrogels for bone regeneration.Journal of advanced research · 2025Review
- Biodegradable Polyesters: Approaches to Increase Degradation Rates for Biomedical Applications.ACS macro letters · 2025Review
- Hydrogel-Based Biomaterials in Spinal Repair: Evaluating Mechanisms for IVDD, SCI, and Dural Regeneration.Journal of multidisciplinary healthcare · 2025Review
- Bioadhesive chitosan hydrogel with dynamic covalent bonds and sustained kartogenin release for endogenous cartilage regeneration.Frontiers in bioengineering and biotechnology · 2025Article
- Evolving functional hydrogel strategies for cartilage engineering: from fundamentals to functional regeneration.Burns & trauma · 2025Review
- Dexamethasone Long-Term Controlled Release from Injectable Dual-Network Hydrogels with Porous Microspheres Immunomodulation Promotes Bone Regeneration.ACS applied materials & interfaces · 2024Article
- Nanoparticle-encapsulated retinoic acid for the modulation of bone marrow hematopoietic stem cell niche.Bioactive materials · 2024Article
- Collagen Type II-Based Injectable Materials for In situ Repair and Regeneration of Articular Cartilage Defect.Biomaterials research · 2024Article
- Advanced Hydrogel-Based Strategies for Enhanced Bone and Cartilage Regeneration: A Comprehensive Review.Gels (Basel, Switzerland) · 2023Review
- Injectable pH and Thermo-Responsive Hydrogel Scaffold with Enhanced Osteogenic Differentiation of Preosteoblasts for Bone Regeneration.Pharmaceutics · 2023Article
- Application of Silk-Fibroin-Based Hydrogels in Tissue Engineering.Gels (Basel, Switzerland) · 2023Review
- Injectable Colloidal Hydrogels ofBiomacromolecules · 2023Article
- Injectable antibacterial Ag-HA/ GelMA hydrogel for bone tissue engineering.Frontiers in bioengineering and biotechnology · 2023Article
- Recent advancements of miRNAs in the treatment of bone diseases and their delivery potential.Current research in pharmacology and drug discovery · 2023Review
- Enhanced bone regeneration via local low-dose delivery of PTHFrontiers in bioengineering and biotechnology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Tissue engineering, using a combination of living cells, bioactive molecules, and three-dimensional porous scaffolds, is a promising alternative to traditional treatments such as the use of autografts and allografts for bone and cartilage tissue regeneration. Scaffolds, in this combination, can be applied either through surgery by implantation of cell-seeded pre-fabricated scaffolds, or through injection of a solidifying precursor and cell mixture, or as an injectable cell-seeded pre-fabricated scaffold. In situ forming and pre-fabricated injectable scaffolds can be injected directly into the defect site with complex shape and critical size in a minimally invasive manner. Proper and homogeneous distribution of cells, biological factors, and molecular signals in these injectable scaffolds is another advantage over pre-fabricated scaffolds. Due to the importance of injectable scaffolds in tissue engineering, here different types of injectable scaffolds, their design challenges, and applications in bone and cartilage tissue regeneration are reviewed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.