Evidence map›Paper›PMID 35420388›Full record

Observational studyClinical reviews in allergy & immunology2023

Real-Life Effectiveness of Benralizumab, Mepolizumab and Omalizumab in Severe Allergic Asthma Associated with Nasal Polyps.

Angelica Tiotiu, Paula Mendez-Brea, Iulia Ioan, Rodrigo Romero-Fernandez, Jean Philippe Oster, Thi-Cam-Tu Hoang, Pauline Roux, Diana Carolina Ochoa-Gutierrez, Philippe Bonniaud, Frederic de Blay and 1 more

Abstract readComparative StudyMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical reviews in allergy & immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Modifying the course of asthma: mechanisms and strategies for clinical remission.Current opinion in allergy and clinical immunology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Biologic Therapies across Nasal Polyp Subtypes.Journal of personalized medicine · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Angelica TiotiuDepartment of Pulmonology, University Hospital of Nancy, 9 Rue du Morvan, 54500, Vandoeuvre-Les-Nancy, Nancy, France. angelica.tiotiu@yahoo.com.
Paula Mendez-BreaDepartment of Allergy, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.
Iulia IoanDevelopment, Adaptation and Disadvantage, Cardiorespiratory Regulations and Motor Control (EA 3450 DevAH), University of Lorraine, Nancy, France.
Rodrigo Romero-FernandezDepartment of Medicine, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.
Jean Philippe OsterDepartment of Pulmonology, Hospital of Colmar, Colmar, France.
Thi-Cam-Tu HoangDepartment of Pulmonology, Hospital of Colmar, Colmar, France.
Pauline RouxDepartment of Pulmonology, University Hospital of Besançon, Besançon, France.
Diana Carolina Ochoa-GutierrezDepartment of Pulmonology-Allergology, University Hospital of Strasbourg, Strasbourg, France.
Philippe BonniaudDepartment of Pulmonary Medicine and Intensive Care Unit, University Hospital of Dijon, Dijon, France.
Frederic de BlayDepartment of Pulmonology-Allergology, University Hospital of Strasbourg, Strasbourg, France.
Francisco-Javier Gonzalez-BarcalaDepartment of Respiratory Medicine, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.
Universidade de Santiago de Compostela · ESCentre Hospitalier Régional et Universitaire de Nancy · FRHopitaux Civils de Colmar · FRUniversité de Strasbourg · FRCentre Hospitalier Universitaire de Besançon · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological therapies are available for the treatment of the severe allergic asthma (SAA) with blood eosinophil count ≥ 0.3 × 10

Indexed as

Anti-Asthmatic AgentsAntibodies, Monoclonal, HumanizedAsthmaNasal PolypsHumansOmalizumabRetrospective StudiesAnti-Asthmatic AgentsAntibodies, Monoclonal, HumanizedbenralizumabmepolizumabOmalizumabBiological therapiesComparative analysisEffectivenessNasal polyposisSevere allergic asthma

Identifiers

PMID35420388
OpenAlexW4223935457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.