Evidence map›Paper›PMID 35419666›Full record

ArticleEuropean journal of applied physiology2022

Aging alters gastrocnemius muscle hemoglobin oxygen saturation (StO

Michael Holmes, Panagiotis Koutakis, Ahmed Ismaeel

Abstract read
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Article in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Molecular Framework of the Onset and Progression of Skeletal Muscle Aging.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael HolmesMax E, Wastl Human Performance Laboratory, Department of Health and Kinesiology, Purdue University, West Lafayette, IN, USA.
Panagiotis KoutakisDepartment of Biology, Baylor University, Waco, TX, USA.
Ahmed IsmaeelDepartment of Biology, Baylor University, Waco, TX, USA. ahmed.ismaeel@uky.edu.ORCID http://orcid.org/0000-0003-4025-3945

Funding

The Role of microRNA-210 in regulating oxidative stress in patients with peripheral artery diseaseR01AG064420 · NIA · UNIVERSITY OF WEST FLORIDA · PI KOUTAKIS, PANAGIOTIS · 2019 to 2023
$3.3M
NIA NIH HHS R01 AG064420NIA NIH HHS R01AG064420
6 · The paper itself

Abstract

purposeFunctional limitations during exercise from alterations in the balance of oxygen supply and demand-as reported by lower tissue oxygen saturation and longer recovery time-are well documented in clinical populations. We aimed to assess changes in skeletal muscle hemoglobin oxygen saturation (StO

methodsWe recruited healthy male and female participants (n = 101) from three age ranges-young (18-39 years), middle age (40-65 years), and older (> 65 years)-to complete exercise tests commonly used in clinical populations. Using near-infrared spectroscopy (NIRS) we assessed StO

resultsMinimum StO

conclusionOur study provides evidence that aging, even in otherwise healthy individuals, negatively impacts muscle StO

Indexed as

Oxygen ConsumptionOxygen SaturationAdolescentAdultAgedAgingFemaleHemoglobinsHumansInfantInfant, NewbornMaleMiddle AgedMuscle, SkeletalOxygenYoung AdultHemoglobinsOxygenAgingExerciseOxygenationSkeletal muscle

Identifiers

PMID35419666

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.