Evidence map›Paper›PMID 35419464›Full record

ArticleOptica2022

Confocal 3D reflectance imaging through multimode fiber without wavefront shaping.

Szu-Yu Lee, Vicente J Parot, Brett E Bouma, Martin Villiger

Abstract read
In one paragraph

Article in Optica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Szu-Yu LeeHarvard Medical School and Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA.ORCID 0000-0002-9381-3849
Vicente J ParotHarvard Medical School and Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA.ORCID 0000-0002-9261-6667
Brett E BoumaHarvard Medical School and Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA.
Martin VilligerHarvard Medical School and Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA.ORCID 0000-0003-3819-1271

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Jacqueline Namati · 2012 to 2026
$22.4M
NIBIB NIH HHS P41 EB015903
6 · The paper itself

Abstract

Imaging through optical multimode fiber (MMF) has the potential to enable hair-thin endoscopes that reduce the invasiveness of imaging deep inside tissues and organs. Active wavefront shaping and fluorescent labeling have recently been exploited to overcome modal scrambling and enable MMF imaging. Here, we present a computational approach that circumvents the need for active wavefront control and exogenous fluorophores. We demonstrate the reconstruction of depth-gated confocal images through MMF using a raster-scanned, focused input illumination at the fiber proximal end. We show the compatibility of this approach with quantitative phase, dark-field, and polarimetric imaging. Computational imaging through MMF opens a new pathway for minimally invasive imaging in medical diagnosis and biological investigations.

Identifiers

PMID35419464
PMCPMC9005109

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.