Evidence map›Paper›PMID 35419346›Full record

ArticleFrontiers in chemistry2022

Fabrication of Naturally Derived Double-Network Hydrogels With a Sustained Aspirin Release System for Facilitating Bone Regeneration.

Wenfeng Zhu, Rui Chen, Weiheng Wang, Yi Liu, Changgui Shi, Songjun Tang, Guoke Tang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wenfeng ZhuDepartment of Orthopedics, Shanghai Post and Telecommunication Hospital, Shanghai, China.
Rui ChenDepartment of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Weiheng WangDepartment of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Yi LiuDepartment of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Changgui ShiDepartment of Orthopedics, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Songjun TangDepartment of Orthopedics, Shanghai Post and Telecommunication Hospital, Shanghai, China.
Guoke TangDepartment of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.
Second Military Medical University · CNShanghai First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous efforts on pursuit of effective drug delivery systems for engineering hydrogel scaffolds is considered a promising strategy for the bone-related diseases. Here, we developed a kind of acetylsalicylic acid (aspirin, ASA)-based double-network (DN) hydrogel containing the positively charged natural chitosan (CS) and methacrylated gelatin (GelMA) polymers. Combination of physical chain-entanglement, electrostatic interactions, and a chemically cross-linked methacrylated gelatin (GelMA) network led to the formation of a DN hydrogel, which had a suitable porous structure and favorable mechanical properties. After

Indexed as

aspirinbone regenerationDN hydrogeldrug deliveryGelMA

Identifiers

PMID35419346
PMCPMC8995466
OpenAlexW4220902750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.