ArticleFrontiers in pediatrics2022
Increased Risk for Thromboembolism After Fontan Surgery: Considerations for Thromboprophylaxis.
Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Optimal Strategy for Thromboprophylaxis in Fontan Circulation: A Systematic Review and Meta-analysis with a Focus on Ethnic Differences.Pediatric cardiology · 2026Pooled it
- Impact of Respiratory Mechanics on Venous Return in Single Ventricle Physiology: A Clinical Imaging Study.JACC. Basic to translational science · 2026Article
- Changes in pharmacotherapy in adults with Fontan circulation and associations with outcomes.International journal of cardiology. Congenital heart disease · 2026Article
- Prothrombin G20210A and Factor V Leiden Variants Are Not Associated With Thrombotic Events in Congenital Heart Disease: An Observational Trial.Journal of the American Heart Association · 2026Observational
- Evaluating the Impact of an Institutional Practice Change from Warfarin to Therapeutic Rivaroxaban Post-Fontan Operation.Pediatric cardiology · 2025Article
- Real-World Use and Outcomes of Apixaban for Early Post-Surgical Fontan Thromboprophylaxis.Pediatric cardiology · 2025Article
- Cardiac Medication Prescription Pattern and Association With Transplant-free Survival in the Adult Fontan Population.JACC. Advances · 2025Article
- Article
- Case report: a thrombus to remember: a case of warfarin non-compliance in a total cavopulmonary circulation patient.European heart journal. Case reports · 2025Article
- Complex Management of Thromboembolism in Double-Outlet Right Ventricle.JACC. Case reports · 2025Article
- Renal Infarction Following Anticoagulant Discontinuation in a Pediatric Patient With Congenital Heart Disease.Cureus · 2025Article
- Thromboprophylaxis strategies for patients with a Fontan palliation: practice in the NHS.The British journal of cardiology · 2025Article
- Sleep disordered breathing and adult congenital heart disease.International journal of cardiology. Congenital heart disease · 2024Review
- Association between warfarin use and thromboembolic events in patients post-Fontan operation: propensity-score overlap weighting analyses.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024Article
- Novel percutaneous aspiration thrombectomy in Fontan conduit obstruction with cardiogenic shock. Case report.International journal of cardiology. Congenital heart disease · 2024Article
- Utility of the Total Thrombus-Formation Analysis System as a Tool for Evaluating Thrombogenicity and Monitoring Antithrombotic Therapy in Pediatric Fontan Patients.Pediatric cardiology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Fontan circulation introduces an increased risk of thromboembolism which is associated with substantial mortality and morbidity. Adverse outcomes of thromboembolic complications post-Fontan surgery vary in both nature and severity, ranging from local tissue infarction and pulmonary embolism to Fontan failure and ischemic stroke. Furthermore, recent studies have identified that subclinical stroke is common yet underdiagnosed in Fontan patients. Fontan patients are commonly treated with antiplatelet agents and/or anticoagulants as primary thromboprophylaxis. Optimal thromboprophylaxis management in the Fontan population is still unclear, and clinical consensus remains elusive despite the growing literature on the subject. This perspective will describe the nature of thromboembolism post-Fontan surgery and provide evidence for the use of both current and emerging thromboprophylaxis options for children and adults living with Fontan circulation.
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Registered trials
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