Evidence map›Paper›PMID 35419297›Full record

ArticleFrontiers in cellular and infection microbiology2022

Mixed Vaginitis in the Third Trimester of Pregnancy Is Associated With Adverse Pregnancy Outcomes: A Cross-Sectional Study.

Huanrong Li, Mengting Dong, Wenjuan Xie, Wenhui Qi, Fei Teng, Huiyang Li, Ye Yan, Chen Wang, Cha Han, Fengxia Xue

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Article
  6. Complete genome sequence of vaginal swab isolateMicrobiology resource announcements · 2025
    Article
  7. Article
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  9. Placental Molecular Expression of Different Pathogenic Vaginal Infections.International journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Huanrong LiDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Mengting DongDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Wenjuan XieDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Wenhui QiDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Fei TengDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Huiyang LiDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Ye YanDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Chen WangDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Cha HanDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Fengxia XueDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixed vaginitis is a complex vaginal dysbiosis that differs from single vaginitis. Vaginitis in the third trimester may lead to adverse maternal and neonatal outcomes. The clinical characteristics, microbiological characteristics, and adverse pregnancy outcomes of mixed vaginitis in late pregnancy are worth studying. Therefore, this study investigated the clinical and microbiological characteristics of vaginitis and adverse pregnancy outcomes of patients with mixed vaginitis. We studied 1,674 women in late pregnancy who attended the Tianjin Medical University General Hospital from November, 2019 to October, 2021. We administered standardized questionnaires, performed vaginal examination and sampling plus microscope examinations, and assessed follow-up pregnancy outcomes. We cultured the vaginal discharge of the patients with mixed vaginitis to isolate pathogens and performed antimicrobial susceptibility tests of the isolated pathogens. For the patients with peripartum infection, we collected a sample to isolate pathogens. Among the 1,674 women, 66 (3.9%) had mixed vaginitis. The independent risk factor for mixed vaginitis in late pregnancy was a history of vaginitis during early and middle pregnancy (OR = 5.637, 95% CI: 3.314-9.580). The signs of vaginal erythema (63.6%

Indexed as

VaginitisVaginosis, BacterialVulvovaginitisCross-Sectional StudiesDysbiosisEscherichia coliFemaleHumansPregnancyPregnancy OutcomePregnancy Trimester, Thirdbacterial vaginosismixed vaginitispathogenpregnancy outcomesthird trimester

Identifiers

PMID35419297
PMCPMC8995747
OpenAlexW4221101360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.