Evidence map›Paper›PMID 35419165›Full record

ArticleOxidative medicine and cellular longevity2022

Hinokitiol Protects Cardiomyocyte from Oxidative Damage by Inhibiting GSK3

Hongkai Xiao, Siyu Liang, Qinhong Cai, Jinghu Liu, Liang Jin, Zhengfei Yang, Xiaochao Chen

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  7. Article
  8. The Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases.Oxidative medicine and cellular longevity · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Hongkai XiaoThe Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou 511300, China.ORCID https://orcid.org/0000-0002-8222-8417
Siyu LiangThe Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou 511300, China.ORCID https://orcid.org/0000-0003-1887-0197
Qinhong CaiThe Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou 511300, China.ORCID https://orcid.org/0000-0002-0825-1715
Jinghu LiuThe Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou 511300, China.ORCID https://orcid.org/0000-0002-9798-1639
Liang JinThe Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou 511300, China.ORCID https://orcid.org/0000-0002-0896-6964
Zhengfei YangSun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 Yan Jiang Xi Road, Guangzhou 510120, China.ORCID https://orcid.org/0000-0001-9793-6910
Xiaochao ChenThe Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou 511300, China.ORCID https://orcid.org/0000-0002-7662-5766
Guangzhou Medical University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More and more attention has been paid to the use of traditional phytochemicals. Here, we first verified the therapeutic potential of a natural bioactive compound called Hinokitiol in myocardial ischemia reperfusion injury. Hinokitiol exerts cardioprotective effect through inhibition of GSK-3

Indexed as

Myocardial Reperfusion InjuryMyocytes, CardiacApoptosisAutophagyGlycogen Synthase Kinase 3 betaHumansMonoterpenesOxidative StressTropolonebeta-thujaplicinGlycogen Synthase Kinase 3 betaMonoterpenesTropolone

Identifiers

PMID35419165
PMCPMC9001072
OpenAlexW4225859691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.