Evidence map›Paper›PMID 35419158›Full record

ArticleThe Neurohospitalist2022

Isolated High-Grade Malignancy of the Spinal Cord Presenting as Longitudinally Extensive Transverse Myelitis.

Lucas Horta, Deepti Virmani, K H Vincent Lau, Pria Anand

Open access · greenAbstract read
In one paragraph

Article in The Neurohospitalist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. H3Journal of clinical medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lucas HortaBoston Medical Center, Boston University School of Medicine, Boston, MA, USA.ORCID https://orcid.org/0000-0002-5824-5815
Deepti VirmaniBoston Medical Center, Boston University School of Medicine, Boston, MA, USA.
K H Vincent LauBoston Medical Center, Boston University School of Medicine, Boston, MA, USA.ORCID https://orcid.org/0000-0003-1416-5589
Pria AnandBoston Medical Center, Boston University School of Medicine, Boston, MA, USA.ORCID https://orcid.org/0000-0002-7421-7750
Boston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article characterizes 2 cases of longitudinally extensive transverse myelitis (LETM) that did not respond to immunotherapy and were diagnosed by biopsy as primary central nervous system (CNS) malignancies. Diffuse H3 K27M-mutant glioma is a recently described entity with very few cases of isolated spinal disease described in adults. Primitive neuroectodermal tumor is similarly uncommon in the spinal cord. Malignancies should be considered in patients who fail to improve with immunomodulatory therapy. We believe the experiences of our center will raise awareness about that point, broaden the existing understanding of the diagnostic approach to LETM, and highlight the need for additional studies.

Indexed as

autoimmune diseases of the nervous systemclinical specialtymyelitisnervous system neoplasmsneuromyelitis opticaneurooncologyspinal cord diseasesspinal cord neoplasmstransverse

Identifiers

PMID35419158
PMCPMC8995616
OpenAlexW3201623503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.