Evidence map›Paper›PMID 35419150›Full record

ArticleThe Neurohospitalist2022

Secondary Hemophagocytic Lymphohistiocytosis Causing Hemorrhagic Encephalomyelitis and Spinal Subarachnoid Hemorrhage: A Case Report.

Matthew R Woodward, Margaret S Ferris, Guillermo Rivell, Laura Malone, Tara M Dutta, Haroon Ahmad, Nicholas A Morris

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Neurohospitalist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Matthew R WoodwardDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-1749-4356
Margaret S FerrisDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0001-7767-0705
Guillermo RivellDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Laura MaloneDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0001-5894-7051
Tara M DuttaDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.
Haroon AhmadDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.
Nicholas A MorrisDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-1270-9805
University of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We are writing to present an interesting and novel case from our practice of a patient who presented with altered mental status and a rapidly progressive paraplegia as well as high fevers and pancytopenia. A bone marrow biopsy was diagnostic of hemophagocytic lymphohistiocytosis (HLH) and MRI showed hemorrhagic encephalitis and spinal subarachnoid hemorrhage. This case demonstrates the diverse neurological symptoms with which HLH presents, including spinal cord pathology. The astute neurologist should consider this diagnosis in the appropriate clinical context and diagnosis may require imaging to the complete neuraxis.

Indexed as

case reporthemophagocytic lymphohistiocytosisspinal subarachnoid hemorrhage

Identifiers

PMID35419150
PMCPMC8995611
OpenAlexW3201380223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.