Evidence map›Paper›PMID 35419113›Full record

ArticleJournal of medicine and life2022

Vasomotor menopausal disorders as a possible result of dysfunction of the microbiota-intestine-brain axis.

Oksana Mykolaivna Pavlovska, Kateryna Mykolaivna Pavlovska, Svitlana Mykolaivna Heryak, Stefan Volodymyrovych Khmil, Mariya Stefanivna Khmil

Open access · diamondAbstract read
In one paragraph

Article in Journal of medicine and life, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. International journal of molecular medicine · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Oksana Mykolaivna PavlovskaDepartment of Obstetrics and Gynecology, Odessa National Medical University, Odessa, Ukraine.ORCID https://orcid.org/0000-0001-9549-9032
Kateryna Mykolaivna PavlovskaDepartment of Internal Medicine No.1-Cardiovascular Pathology, Odessa National Medical University, Odessa, Ukraine.ORCID https://orcid.org/0000-0002-4869-8212
Svitlana Mykolaivna HeryakSecond Department of Obstetrics and Gynecology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.ORCID https://orcid.org/0000-0002-7894-1009
Stefan Volodymyrovych KhmilFirst Department of Obstetrics and Gynecology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.ORCID https://orcid.org/0000-0003-3447-4282
Mariya Stefanivna KhmilFirst Department of Obstetrics and Gynecology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.ORCID https://orcid.org/0000-0002-9263-2069
Odessa National Medical University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study involved clinical and laboratory examination of 54 women with vasomotor menopausal disorders divided into 3 subgroups depending on the duration of symptoms (not more than 12 months, about 3 years, from 5 to 7 years). The control group included 21 patients without vasomotor disorders during the menopausal period. Data from the general and obstetric-gynecological anamnesis and the results of objective and general clinical examinations were analyzed. To assess the state of intestinal microbiocenosis in patients, a bacteriological study of feces was used according to modern methods. In women with menopausal vasomotor disorders, chronic arterial hypertension, overweight, diabetes mellitus, chronic enterocolitis, and chronic pyelonephritis prevailed among somatic diseases. The study also revealed that these patients had a pronounced imbalance of the intensive microbiota, which was characterized by a significant decrease in the main representatives of the obligate microflora (Bifidobacterium, Lactobacillus) and an increase in the number of opportunistic strains (Klebsiella and Clostridiodes difficile). Considering modern concepts, a change in the microbial composition of the intestine may be one of the possible trigger factors for the occurrence of vasomotor menopausal disorders. Further research will clarify the influence of the microbiome on the formation of the pathological menopausal symptom complex and improve the preventive and therapeutic measures in this category of women.

Indexed as

MenopauseMicrobiotaBrainFemaleHumansIntestinesPregnancySyndromeclimacteric periodintestinal microbiotamenopausal vasomotor disorders

Identifiers

PMID35419113
PMCPMC8999096
OpenAlexW4224033913

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.