Evidence map›Paper›PMID 35419037›Full record

ArticleFrontiers in genetics2022

Genome-Wide Marker Data-Based Comparative Population Analysis of Szeklers From Korond, Transylvania, and From Transylvania Living Non-Szekler Hungarians.

Valerián Ádám, Zsolt Bánfai, Katalin Sümegi, Gergely Büki, András Szabó, Lili Magyari, Attila Miseta, Miklós Kásler, Béla Melegh

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Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Valerián ÁdámDepartment of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary.
Zsolt BánfaiDepartment of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary.
Katalin SümegiDepartment of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary.
Gergely BükiDepartment of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary.
András SzabóDepartment of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary.
Lili MagyariDepartment of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary.
Attila MisetaDepartment of Laboratory Medicine, Medical School, University of Pécs, Pécs, Hungary.
Miklós KáslerNational Institute of Oncology, Budapest, Hungary.
Béla MeleghDepartment of Medical Genetics, Medical School, University of Pécs, Pécs, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide genotype data from 48 carefully selected population samples of Transylvania-living Szeklers and non-Szekler Hungarians were analyzed by comparative analysis. Our analyses involved contemporary Hungarians living in Hungary, other Europeans, and Eurasian samples counting 530 individuals altogether. The source of the Szekler samples was the commune of Korond, Transylvania. The analyzed non-Szekler Hungarian samples were collected from villages with a history dating back to the era of the Árpád Dynasty. Population structure by principal component analysis and ancestry analysis also revealed a great within-group similarity of the analyzed Szeklers and non-Szekler Transylvanian Hungarians. These groups also showed similar genetic patterns with each other. Haplotype analyses using identity-by-descent segment discovering tools showed that average pairwise identity-by-descent sharing is similar in the investigated populations, but the Korond Szekler samples had higher average sharing with the Hungarians from Hungary than non-Szekler Transylvanian Hungarians. Average sharing results showed that both groups are isolated compared to other Europeans, and pointed out that the non-Szekler Transylvanian Hungarian inhabitants of the investigated Árpád Age villages are more isolated than investigated Szeklers from Korond. This was confirmed by our autozygosity analysis as well. Identity-by-descent segment analyses and 4-population tests also confirmed that these Hungarian-speaking Transylvanian ethnic groups are strongly related to Hungarians living in Hungary.

Indexed as

genome-wide dataidentical by descentpopulation geneticsSzeklersTransylvania

Identifiers

PMID35419037
PMCPMC9000985

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