ArticleJournal of atherosclerosis and thrombosis2023
Body Mass Index and Mortality from Nonrheumatic Aortic Valve Disease among Japanese Men and Women.
Article in Journal of atherosclerosis and thrombosis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors at 5 institutions in 3 countries.
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Abstract
aimWe aimed to examine the impact of overweight and obesity on mortality from nonrheumatic aortic valve disease.
methodsIn the Japan Collaborative Cohort Study, we analyzed data of 98,378 participants aged 40-79 years, with no history of coronary heart disease, stroke, or cancer at baseline (1988-1990) and who completed a lifestyle questionnaire including height and body weight; they were followed for mortality until the end of 2009. The Cox proportional hazards model was used to calculate the multivariable hazard ratios (HRs) with 95% confidence intervals (CIs) of nonrheumatic aortic valve disease mortality according to body mass index (BMI) after adjusting for potential confounding factors.
resultsDuring the median 19.2 years follow-up, 60 deaths from nonrheumatic aortic valve disease were reported. BMI was positively associated with the risk of mortality from nonrheumatic aortic valve disease; the multivariable HRs (95% CIs) were 0.90 (0.40-2.06) for persons with BMI <21 kg/m
conclusionsOverweight and obesity may be independent risk factors for nonrheumatic aortic valve disease mortality in Asian populations.
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