Evidence map›Paper›PMID 35418486›Full record

ArticleHeart (British Cardiac Society)2022

Pregnancy-related cardiovascular conditions and outcomes in a United States Medicaid population.

Simone Marschner, Amy von Huben, Sarah Zaman, Harmony R Reynolds, Vincent Lee, Preeti Choudhary, Laxmi S Mehta, Clara K Chow

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heart (British Cardiac Society), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Simone MarschnerWestmead Applied Research Centre, The University of Sydney, Westmead, New South Wales, Australia simone.marschner@sydney.edu.au.ORCID 0000-0002-5484-9144
Amy von HubenWestmead Applied Research Centre, The University of Sydney, Westmead, New South Wales, Australia.
Sarah ZamanWestmead Applied Research Centre, The University of Sydney, Westmead, New South Wales, Australia.ORCID 0000-0001-6289-583X
Harmony R ReynoldsGrossman School of Medicine, Charney Division of Cardiology, NYU, New York, New York, USA.
Vincent LeeWestmead Applied Research Centre, The University of Sydney, Westmead, New South Wales, Australia.
Preeti ChoudharyDepartment of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia.
Laxmi S MehtaDivision of Cardiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Clara K ChowWestmead Applied Research Centre, The University of Sydney, Westmead, New South Wales, Australia.ORCID 0000-0003-4693-0038

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to examine the incidence of pregnancy-related cardiometabolic conditions and severe cardiovascular outcomes, and their relationship in US Medicaid-funded women.

methodsMedicaid is a government-sponsored health insurance programme for low-income families in the USA. We report the incidence of pregnancy-related cardiometabolic conditions (hypertensive disorders and diabetes in, or complicated by, pregnancy) and severe cardiovascular outcomes (myocardial infarction, stroke, acute heart failure, cardiomyopathy, cardiac arrest, ventricular fibrillation, ventricular tachycardia, aortic dissection/aneurysm and peripheral vascular disease) among Medicaid-funded women with a birth (International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) diagnosis code O80 or O82) over the period January 2015-June 2019, from the states of Georgia, Ohio and Indiana. In this cross-sectional cohort, we examined the relationship between pregnancy-related cardiometabolic conditions and severe cardiovascular outcomes from pregnancy through to 60 days after birth using multivariable models.

resultsAmong 74 510 women, mean age 26.4 years (SD 5.5), the incidence per 1000 births of pregnancy-related cardiometabolic conditions was 224.3 (95% CI 221.3 to 227.3). The incidence per 1000 births of severe cardiovascular conditions was 10.8 (95% CI 10.1 to 11.6). Women with pregnancy-related cardiometabolic conditions were at greater risk of having a severe cardiovascular condition with an age-adjusted OR of 3.1 (95% CI 2.7 to 3.5).

conclusionThis US cohort of Medicaid-funded women have a high incidence of severe cardiovascular conditions during pregnancy. Cardiometabolic conditions of pregnancy conferred threefold higher odds of severe cardiovascular outcomes.

Indexed as

Cardiovascular DiseasesHeart FailureAdultArrhythmias, CardiacCross-Sectional StudiesFemaleHumansMedicaidPovertyPregnancyUnited StatesDiabetes MellitusHeart Failure, SystolicHypertensionPregnancyStroke

Identifiers

PMID35418486
PMCPMC9484386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.