Evidence map›Paper›PMID 35418202›Full record

ArticleScientific reports2022

Differentiating amnestic from non-amnestic mild cognitive impairment subtypes using graph theoretical measures of electroencephalography.

Jae-Gyum Kim, Hayom Kim, Jihyeon Hwang, Sung Hoon Kang, Chan-Nyoung Lee, JunHyuk Woo, Chanjin Kim, Kyungreem Han, Jung Bin Kim, Kun-Woo Park

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jae-Gyum Kim *Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Hayom Kim *Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Jihyeon HwangDepartment of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Sung Hoon KangDepartment of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Chan-Nyoung LeeDepartment of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
JunHyuk WooLaboratory of Computational Neurophysics, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea.
Chanjin KimLaboratory of Computational Neurophysics, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea.
Kyungreem HanLaboratory of Computational Neurophysics, Brain Science Institute, Korea Institute of Science and Technology, Seoul, Republic of Korea.
Jung Bin KimDepartment of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea. kjbin80@korea.ac.kr.
Kun-Woo ParkDepartment of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to explore different patterns of functional networks between amnestic mild cognitive impairment (aMCI) and non-aMCI (naMCI) using electroencephalography (EEG) graph theoretical analysis. The data of 197 drug-naïve individuals who complained cognitive impairment were reviewed. Resting-state EEG data was acquired. Graph analyses were performed and compared between aMCI and naMCI, as well as between early and late aMCI. Correlation analyses were conducted between the graph measures and neuropsychological test results. Machine learning algorithms were applied to determine whether the EEG graph measures could be used to distinguish aMCI from naMCI. Compared to naMCI, aMCI showed higher modularity in the beta band and lower radius in the gamma band. Modularity was negatively correlated with scores on the semantic fluency test, and the radius in the gamma band was positively correlated with visual memory, phonemic, and semantic fluency tests. The naïve Bayes algorithm classified aMCI and naMCI with 89% accuracy. Late aMCI showed inefficient and segregated network properties compared to early aMCI. Graph measures could differentiate aMCI from naMCI, suggesting that these measures might be considered as predictive markers for progression to Alzheimer's dementia in patients with MCI.

Indexed as

Alzheimer DiseaseCognitive DysfunctionNeuroblastomaBayes TheoremElectroencephalographyHumansNeuropsychological Tests

Identifiers

PMID35418202
PMCPMC9008046

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.