Evidence map›Paper›PMID 35418184›Full record

ArticleNature communications2022

Using deep learning to predict abdominal age from liver and pancreas magnetic resonance images.

Alan Le Goallec, Samuel Diai, Sasha Collin, Jean-Baptiste Prost, Théo Vincent, Chirag J Patel

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

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  7. Contextualizing molecular and structural aging across human organs.medRxiv : the preprint server for health sciences · 2025
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  15. Biomarkers of aging.Science China. Life sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alan Le GoallecDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0002-4257-1851
Samuel DiaiDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.
Sasha CollinDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0002-8732-0829
Jean-Baptiste ProstDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0001-9973-727X
Théo VincentDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0002-1723-7405
Chirag J PatelDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA. chirag_patel@hms.harvard.edu.ORCID http://orcid.org/0000-0002-8756-8525
Harvard University · US

Funding

Data science tools to identify robust exposure-phenotype associations for precision medicineR01ES032470 · NIEHS · HARVARD MEDICAL SCHOOL · PI MANRAI, ARJUN KUMAR, PATEL, CHIRAG J. · 2021 to 2025
$3.5M
Big Data Analysis of HIV Risk and Epidemiology in Sub-Saharan AfricaR01AI127250 · NIAID · STANFORD UNIVERSITY · PI BENDAVID, ERAN, PATEL, CHIRAG J. · 2017 to 2020
$2.7M
Increasing the power of GxE detection by using multi-locus genome-wide predictorsR21ES025052 · NIEHS · HARVARD MEDICAL SCHOOL · PI PATEL, CHIRAG J. · 2015 to 2017
$434k
Medical Research Council MC_PC_17228Medical Research Council MC_QA137853NIAID NIH HHS R01 AI127250NIEHS NIH HHS R01 ES032470NIEHS NIH HHS R21 ES025052
6 · The paper itself

Abstract

With age, the prevalence of diseases such as fatty liver disease, cirrhosis, and type two diabetes increases. Approaches to both predict abdominal age and identify risk factors for accelerated abdominal age may ultimately lead to advances that will delay the onset of these diseases. We build an abdominal age predictor by training convolutional neural networks to predict abdominal age (or "AbdAge") from 45,552 liver magnetic resonance images [MRIs] and 36,784 pancreas MRIs (R-Squared = 73.3 ± 0.6; mean absolute error = 2.94 ± 0.03 years). Attention maps show that the prediction is driven by both liver and pancreas anatomical features, and surrounding organs and tissue. Abdominal aging is a complex trait, partially heritable (h_g

Indexed as

Deep LearningImage Processing, Computer-AssistedLiverMagnetic Resonance ImagingNeural Networks, ComputerPancreas

Identifiers

PMID35418184
PMCPMC9007982
OpenAlexW4223643417

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.