ArticleNPJ biofilms and microbiomes2022
Adaptation and phenotypic diversification of Bacillus thuringiensis biofilm are accompanied by fuzzy spreader morphotypes.
Article in NPJ biofilms and microbiomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 13 citations in OpenAlex.
- Ureolytic bacteria for MICP application to iron-rich slag materials for waste stabilization and carbon sequestration.Environmental systems research · 2026Article
- Evolution of genotypic and phenotypic diversity in multispecies biofilms.NPJ biofilms and microbiomes · 2025Article
- Synergistic biodegradation of polyethylene by experimentally evolved bacterial biofilms.The ISME journal · 2025Article
- Presence of a biofilm beneficiary alters the evolutionary trajectory of a biofilm former.The ISME journal · 2025Article
- Sliding motility of Bacillus cereus mediates vancomycin pseudo-resistance during antimicrobial susceptibility testing.The Journal of antimicrobial chemotherapy · 2024Article
- Article
- Emergence of novel non-aggregative variants under negative frequency-dependent selection inmicroLife · 2023Article
- Adaptation of Bacillus thuringiensis to Plant Colonization Affects Differentiation and Toxicity.mSystems · 2021Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
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Abstract
Bacillus cereus group (Bacillus cereus sensu lato) has a diverse ecology, including various species that produce biofilms on abiotic and biotic surfaces. While genetic and morphological diversification enables the adaptation of multicellular communities, this area remains largely unknown in the Bacillus cereus group. In this work, we dissected the experimental evolution of Bacillus thuringiensis 407 Cry- during continuous recolonization of plastic beads. We observed the evolution of a distinct colony morphotype that we named fuzzy spreader (FS) variant. Most multicellular traits of the FS variant displayed higher competitive ability versus the ancestral strain, suggesting an important role for diversification in the adaptation of B. thuringiensis to the biofilm lifestyle. Further genetic characterization of FS variant revealed the disruption of a guanylyltransferase gene by an insertion sequence (IS) element, which could be similarly observed in the genome of a natural isolate. The evolved FS and the deletion mutant in the guanylyltransferase gene (Bt407ΔrfbM) displayed similarly altered aggregation and hydrophobicity compared to the ancestor strain, suggesting that the adaptation process highly depends on the physical adhesive forces.
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