SynthesisBMC endocrine disorders2022
Association between type 2 diabetes (T2D) and tooth loss: a systematic review and meta-analysis.
Synthesis in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Examining the link between tooth loss and multiple health outcomes: a comprehensive synthesis of evidence from meta-analyses.Frontiers in public health · 2026Pooled it
- Laser treatments as an adjunct to non-surgical periodontal therapy in subjects with periodontitis and type 2 diabetes mellitus: a systematic review and meta-analysis.Clinical oral investigations · 2023Pooled it
- 'I Got Dentures in, So at Least I Can Eat Now': Aboriginal and Torres Strait Islander Peoples' Perceptions of and Experiences With Removable Dentures.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2027Article
- Association between tooth loss and kidney function: indirect roles of oxidative stress and systemic inflammation in NHANES 2001-2020.The Saudi dental journal · 2026Article
- Healing Response to Hyaluronic Acid Supplemented with Selected Amino Acids: A Pooled Analysis of Two Clinical Studies.Journal of functional biomaterials · 2026Article
- Tooth extractions and the prevalence of postoperative complications in individuals with and without diabetes: a retrospective cross-sectional study.BMC oral health · 2026Article
- Mapping Tooth Loss at the Tooth Level: Associations with Demographic, Health, and Behavioral Factors.JDR clinical and translational research · 2026Observational
- Tooth Loss and Uncontrolled Diabetes Among Korean Adults With Type 2 Diabetes: Insights From the Korea National Health and Nutrition Examination Survey (KNHANES) 2014-2018.Clinical and experimental dental research · 2026Article
- Bioengineered Teeth and Regenerative Strategies: Advances in Tissue Engineering and Stem Cell Applications.Annals of biomedical engineering · 2026Review
- Association of anterior crossbite and open bite with the number of remaining teeth: A cross-sectional study from the Tohoku medical megabank cohort.Clinical oral investigations · 2026Article
- Exploring the multifaceted roles of beta-defensins in prediabetes: a detailed review.Frontiers in endocrinology · 2026Review
- Type 2 Diabetes Impairs Alveolar Socket Healing: Immunohistochemical Analysis of Del-1, IL-17, RANKL, and OPG Expression in a Rat Model.International journal of dentistry · 2026Article
- Tooth Loss and Cardiovascular Risk Burden in Myocardial Infarction Patients.Journal of clinical medicine · 2025Article
- Integrating Periodontal Care Into Diabetes Management: A Narrative Perspective for Bangladesh With Global Relevance.Health science reports · 2025Article
- Effect of Diabetes Mellitus on Survival and Complication Rates of Tooth-Supported Fixed Dental Prostheses (FDPs): Long-Term Clinical Evaluation.Journal of clinical medicine · 2025Article
- Student-performed periodontal therapy: retrospective cohort study on outcomes and related recommendations for enhancing undergraduate periodontal education.BMC medical education · 2025Article
- Oral Health Disparities in Type 2 Diabetes: Examining the Elevated Risk for Dental Caries-A Comparative Study.Dentistry journal · 2025Article
- Treating Periodontitis Strictly Non-Surgically-A Retrospective Long-Term Analysis of Tooth Loss During Supportive Periodontal Care.Dentistry journal · 2025Article
- Oral health practices and literacy in Hungarian diabetes patients: insights from a pilot-study using a WHO-adapted questionnaire.BMC oral health · 2025Article
- Influencing Factors of Diabetic Patients of on Oral Health-Related Quality of Life: A Scoping Review.Iranian journal of public health · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have assessed the relationship between type 2 diabetes (T2D) and tooth loss; however, results have been inconsistent. Therefore, the present systematic review and meta-analysis of observational studies was designed to examine the association between T2D and tooth loss.
methodsThis systematic review and meta-analysis was conducted based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guideline. We searched all the relevant studies in international databases of Scopus, PubMed, ProQuest, Web of Science, Cochrane Library, and Google scholar search engine until February 2022. The heterogeneity of the studies was calculated using the I
resultsIn the present study, 22 eligible studies were included. Meta-analysis of unadjusted and adjusted results showed that T2D significantly increased the risk of tooth loss, and Odds Ratio (OR) unadjusted was 1.87 (95% CI: 1.62-2.13, p < 0.001), and OR adjusted was 1.20 (95% CI: 1.10-1.30, p < 0.001), respectively. Subgroup analysis based on study design for adjusted OR indicated that in the cohort study (OR: 1.29, 95% CI: 1.07-1.51), in the cross-sectional study (OR: 1.15, 95% CI: 1.06-1.23), and in the case-control study (OR: 5.10, 95% CI: 1.01-9.18) there was a significant association between T2D and tooth loss. Other subgroups analyses showed consistent results and no publication bias existed.
conclusionsThe findings suggest that T2D is associated with increased risk of tooth loss. This conclusion may provide useful evidence for correlated clinical researches.
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