Evidence map›Paper›PMID 35417613›Full record

ArticleJournal of diabetes investigation2022

Association between changes in bodyweight and cardiovascular disease risk factors among obese Japanese patients with type 2 diabetes.

Ran Yoshimura, Tomoko Nakagami, Yukiko Hasegawa, Junko Oya, Tetsuya Babazono

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Prevalence of Metabolic Syndrome in Patients with Type 2 Diabetes in Japan: A Retrospective Cross-Sectional Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ran YoshimuraDivision of Diabetology and Metabolism, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7613-4417
Tomoko NakagamiDivision of Diabetology and Metabolism, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-4376-7212
Yukiko HasegawaDivision of Diabetology and Metabolism, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-0801-8382
Junko OyaDivision of Diabetology and Metabolism, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6413-2606
Tetsuya BabazonoDivision of Diabetology and Metabolism, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0001-8545-3604
Tokyo Women's Medical University · JP

Funding

Tokyo Womens Medical University The 24th Takako Satake Research Grant
6 · The paper itself

Abstract

AIMS/

introductionWe aimed to assess the association between bodyweight reduction and cardiovascular disease risk factors, and to identify the minimum bodyweight reduction associated with significant improvement in cardiovascular disease risk factors among obese Japanese patients with type 2 diabetes. MATERIALS AND

methodsThe cohort comprised 1,753 patients with type 2 diabetes and body mass index ≥25 kg/m

resultsLog-transformed bodyweight change had a significantly positive relationship with log-transformed glycated hemoglobin A1c, triglycerides, low-density lipoprotein cholesterol and systolic blood pressure changes, and a negative relationship with high-density lipoprotein cholesterol, after adjusting for sex, age, duration of diabetes, body mass index, use of glucose-lowering, lipid-lowering and antihypertensive agents, and changes in the use of these medications. A mean change in glycated hemoglobin A1c was significantly improved only in the <-5% group compared with the reference. Mean changes in triglycerides were improved in all groups, and significantly in the <-5% group.

conclusionsBodyweight change was significantly associated with cardiovascular disease risk factor changes, and >5% bodyweight reduction was associated with improved glycated hemoglobin A1c.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Blood GlucoseBody WeightCholesterol, LDLGlycated HemoglobinHeart Disease Risk FactorsHumansJapanObesityRisk FactorsTriglyceridesBlood GlucoseCholesterol, LDLGlycated HemoglobinTriglyceridesBodyweight reductionCardiovascular disease risk factorsType 2 diabetes

Identifiers

PMID35417613
PMCPMC9434567
OpenAlexW4223899457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.