ArticleDevelopmental science2023
Threat and deprivation are associated with distinct aspects of cognition, emotional processing, and psychopathology in children and adolescents.
Article in Developmental science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.
- The Impact of Adverse Childhood Experiences on Cognitive Control Across the Lifespan: A Systematic Review and Meta-analysis of Prospective Studies.Trauma, violence & abuse · 2025Pooled it
- Effects of adverse childhood experiences on behavior in adolescence: Insights from brain imaging and genetic risk.Developmental cognitive neuroscience · 2026Article
- Distinct Associations of Threat and Deprivation With Changes in Affective Control during Adolescence: A Longitudinal Population-Based Study.Developmental science · 2026Article
- Developmental predictors of suicide attempts from childhood to early adulthood: a 15-year prospective cohort study.Lancet regional health. Americas · 2026Article
- The Transdiagnostic Association Between Childhood Trauma and Accelerated Brain Aging in Two Independent Datasets.Schizophrenia bulletin · 2026Article
- Dimensions of Early-Life Adversity and Attention Biases in Childhood and Adolescence: A Systematic Review.Clinical child and family psychology review · 2026Review
- Cognitive ability in childhood predicts adolescent structural and functional brain development: A longitudinal study.Developmental cognitive neuroscience · 2026Article
- Sexual violence against children and adolescents: analysis in peripheral contexts in the metropolis of São Paulo, Brazil.Archives of public health = Archives belges de sante publique · 2026Article
- Domain Generality or Domain Specificity? The Associations Between Family Adversity, Irritability, and Psychopathology in Adolescence.Child psychiatry and human development · 2026Article
- Inhibitory control-related neural pathways of early adversity to internalizing problems in preadolescence.Journal of affective disorders · 2026Article
- Polyvictimization Profiles and Variations in Youth Mental Health Symptoms: A Person-Centered Approach.Child maltreatment · 2026Article
- Brain controllability mediates the effects of early life adversity on adolescent behavior and cognition moderated by genetic risks.Research square · 2026Article
- Testing the Dimensional Model of Adversity and Psychopathology: the Mediating Roles of Executive Functioning and Emotion Regulation.Research on child and adolescent psychopathology · 2026Article
- The genetic risk of mental health disorders in children from diverse population-based cohorts is modulated by poverty.Research square · 2026Article
- Reimagining the biopsychosocial model: hierarchical mechanisms from transdiagnostic to precision psychiatry.Journal of psychiatry & neuroscience : JPN · 2026Review
- Mother infant cortisol levels and maternal childhood adversity.Scientific reports · 2025Article
- The relationship between household economic shocks, depression, and elevated stress-responsive biomarkers among adolescent girls and young women in rural South Africa (HPTN 068).Journal of affective disorders · 2025Article
- Maternal caregiving moderates relations between maternal childhood maltreatment and infant cortisol regulation.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Nonlinear associations between reported childhood trauma and cognitive impairment in schizophrenia spectrum disorders.Schizophrenia research · 2025Article
- Environmental adversity, life-history traits and cognitive functioning in children and adolescents.Royal Society open science · 2025Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 3 countries.
Funding
Abstract
Exposure to childhood adversity has been consistently associated with poor developmental outcomes, but it is unclear whether these associations vary across different forms of adversity. We examined cross-sectional and longitudinal associations between threat and deprivation with cognition, emotional processing, and psychopathology in a middle-income country. The sample consisted of 2511 children and adolescents (6-17 years old) from the Brazilian High-Risk Cohort for Mental Conditions. Parent reports on childhood adversity were used to construct adversity latent constructs. Psychopathology was measured by the Child Behavior Checklist (CBCL) to generate a measure of general psychopathology (the "p" factor). Executive function (EF) and attention orienting toward angry faces were assessed using cognitive tasks. All measures were acquired at two time-points 3 years apart and associations were tested using general linear models. Higher levels of psychopathology were predicted by higher levels of threat cross-sectionally and longitudinally, and by deprivation longitudinally. For EF, worse performance was associated only with deprivation at baseline and follow-up. Finally, threat was associated with attention orienting towards angry faces cross-sectionally, but neither form of adversity was associated with changes over time in attention bias. Our results suggest that threat and deprivation have differential associations with cognitive development and psychopathology. Exposure to adversity during childhood is a complex phenomenon with meaningful influences on child development. Because adversity can take many forms, dimensional models might help to disentangle the specific developmental correlates of different types of early experience. A video abstract of this article can be viewed at https://www.youtube.com/watch?v=uEU0L8exyTM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.