Evidence map›Paper›PMID 35417516›Full record

ArticleArquivos brasileiros de oftalmologia

The nuclear factor E2-related factor 2 and age-related macular degeneration.

Rogil José de Almeida Torres, Rogério João de Almeida Torres, Andréa Luchini, Ana Lúcia Dos Anjos Ferreira

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de oftalmologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rogil José de Almeida TorresUniversidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brazil.ORCID 0000-0002-4371-202X
Rogério João de Almeida TorresDepartamento de Oftalmologia, Hospital Angelina Caron, Campina Grande do Sul, PR, Brazil.
Andréa LuchiniCentro Oftalmológico de Curitiba, Curitiba, PR, Brazil.
Ana Lúcia Dos Anjos FerreiraUniversidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brazil.
Universidade Estadual Paulista (Unesp) · BRCentro Universitário Curitiba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After the discovery of anti-vascular endothelial growth factor agents as treatment of wet age-related macular degeneration, the number of studies with the objective to understand the molecular mechanisms involved in the age-re lated macular degeneration genesis has increased. The importance of the nuclear factor e2-related factor 2 lies in its activation-derived proteins being involved in the maintenance of the redox balance and consequent prevention of degenerative macular disease. This article aims to present the characteristics of nuclear factor e2-related factor 2 and describe the main nuclear factor e2-related factor 2-activated antioxidant enzymes that contribute to the preservation of vision.

Indexed as

Angiogenesis InhibitorsWet Macular DegenerationHumansIntravitreal InjectionsNF-E2-Related Factor 2RanibizumabVision, OcularAngiogenesis InhibitorsNF-E2-Related Factor 2Ranibizumab

Identifiers

PMID35417516
PMCPMC11892469
OpenAlexW4214652009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.