ArticleAmerican journal of respiratory and critical care medicine2022
Rare and Common Variants in
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
7.8field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Common and rare variant analyses reveal genetic factors underlying idiopathic pulmonary fibrosis and its shared aetiology with severe COVID-19.EBioMedicine · 2025Pooled it
- Common single nucleotide polymorphisms associated with idiopathic pulmonary fibrosis: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- Performance of age-adjusted whole genome sequencing telomere length in idiopathic pulmonary fibrosis.American journal of respiratory and critical care medicine · 2026Article
- KIF15 (Kinesin-12): molecular biology, physiological functions, and roles in disease.Journal of cancer research and clinical oncology · 2026Review
- The YY1-KIF15-PRDX1 axis promotes gastric cancer progression by inducing mitochondrial ROS imbalance.Oncogene · 2026Article
- Advances in our understanding of distal progenitors in idiopathic pulmonary fibrosis: implications for novel therapeutics.The European respiratory journal · 2026Review
- Polygenic risk and rare variants in endotypes of idiopathic pulmonary fibrosis: a genetic analysis of population-based and case-control cohorts.The Lancet. Respiratory medicine · 2026Article
- Human respiratory airway progenitors derived from pluripotent cells generate alveolar epithelial cells and model pulmonary fibrosis.Nature biotechnology · 2026Article
- Rare genetic variant risks in patients with sepsis-associated acute respiratory distress syndrome.Respiratory research · 2026Article
- Contribution of dominant and recessive model effects to the genetic architecture of Idiopathic Pulmonary Fibrosis.medRxiv : the preprint server for health sciences · 2026Article
- Age-dependent Genetic Risk in Pulmonary Fibrosis Patients and Relatives.medRxiv : the preprint server for health sciences · 2026Article
- Genetic Familial Interstitial Lung Disease.Clinics in chest medicine · 2025Review
- A tiered strategy to identify relevant genetic variants in familial pulmonary fibrosis: a proof of concept for the clinical practice.European journal of human genetics : EJHG · 2025Article
- DNA methylome biomarkers of rheumatoid arthritis-associated interstitial lung disease reflecting lung fibrosis pathways, an exploratory case-control study.Scientific reports · 2025Article
- Viewpoint: Pre- and post-lung transplant considerations for patients with ultra-short telomere length.The European respiratory journal · 2025Article
- Dysregulated alveolar epithelial cell progenitor function and identity in Hermansky-Pudlak syndrome.JCI insight · 2024Article
- Rare genetic interstitial lung diseases: a pictorial essay.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Causal relationship between circulating glutamine levels and idiopathic pulmonary fibrosis: a two-sample mendelian randomization study.BMC pulmonary medicine · 2024Article
- Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.American journal of respiratory and critical care medicine · 2024Review
- A Test to Comprehensively Capture the Known Genetic Component of Familial Pulmonary Fibrosis.American journal of respiratory cell and molecular biology · 2024Article
Corrections and comments
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Authors and funding
21 authors at 11 institutions in 4 countries.
David ZhangDepartment of Medicine and.ORCID 0000-0002-2983-9796
Gundula PovysilInstitute for Genomic Medicine, Irving Medical Center, Columbia University, New York, New York.ORCID 0000-0003-4625-5909
Philippe H KobeissyDepartment of Medicine and.
Qi LiDepartment of Medicine and.
Binhan WangDepartment of Medicine and.
Mason AmelotteDepartment of Medicine and.
Hager JaouadiDepartment of Medicine and.ORCID 0000-0002-6806-0072
Chad A NewtonDepartment of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0001-5256-9029
Toby M MaherKeck School of Medicine, University of Southern California, Los Angeles, California.ORCID 0000-0001-7192-9149
Philip L MolyneauxNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Imre NothDepartment of Medicine, School of Medicine, University of Virginia, Charlottesville, Virginia.
Fernando J MartinezDepartment of Medicine, Weill-Cornell Medical Center, New York, New York.ORCID 0000-0002-2412-3182
Ganesh RaghuDepartment of Medicine, University of Washington Medical Center, Seattle, Washington.ORCID 0000-0001-7506-6643
Jamie L ToddDepartment of Medicine, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0003-4247-3693
Scott M PalmerDepartment of Medicine, Duke University Medical Center, Durham, North Carolina.
Carolina HaefligerCentre for Genomics Research, Discovery Sciences, and.ORCID 0000-0002-5095-5716
Adam PlattTranslational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom; and.ORCID 0000-0002-3455-1789
Slavé PetrovskiCentre for Genomics Research, Discovery Sciences, and.
Joseph A GarciaDepartment of Medicine and.
David B GoldsteinDepartment of Medicine and.
Christine Kim GarciaDepartment of Medicine and.ORCID 0000-0002-0771-1249
Columbia University Irving Medical Center · USClinical Research Institute · USAstraZeneca (United Kingdom) · GBCornell University · USDiscovery Centre · CAImperial College London · GBThe University of Melbourne · AUThe University of Texas Southwestern Medical Center · USUniversity of Southern California · USUniversity of Virginia · USUniversity of Washington Medical Center · US
Funding
UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases studyUH3HL145266 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARTINEZ, FERNANDO J, NOTH, IMRE · 2021 to 2025
$11.6MPulmonary Fibrosis and Telomerase DysfunctionR01HL093096 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI GARCIA, CHRISTINE KIM · 2009 to 2024
$6.9MArchitectural structure and regulation of TOLLIP in IPFR01HL130796 · NHLBI · UNIVERSITY OF VIRGINIA · PI NOTH, IMRE · 2016 to 2019
$3.1MMechanistic Studies and Translational Applications of Stress Signaling in AnemiaR01HL130142 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI GARCIA, JOSEPH ANTHONY · 2016 to 2019
$1.6MMolecular Markers of Idiopathic Pulmonary Fibrosis ProgressionK23HL148498 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI NEWTON, CHAD ALAN · 2020 to 2024
$891kDynamic Regulation of Erythropoietin Gene Expression in Mammals.I01BX000446 · VA · VA NORTH TEXAS HEALTH CARE SYSTEM · PI Joseph Anthony Garcia · 2009 to 2026
–BLRD VA I01 BX000446NCATS NIH HHS UL1 TR001105NHLBI NIH HHS K23 HL148498NHLBI NIH HHS R01 HL093096NHLBI NIH HHS R01 HL130142NHLBI NIH HHS R01 HL130796NHLBI NIH HHS UH3 HL145266
Abstract
PubMed holds no abstract for this paper.
Indexed as
Idiopathic Pulmonary FibrosisKinesinsTelomeraseExomeHumansTelomereKIF15 protein, humanKinesinsTelomerasecell proliferationgeneticsIPFKIF15spindle
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.