Evidence map›Paper›PMID 35417285›Full record

ReviewHuman vaccines & immunotherapeutics2022

Longevity of immunity following COVID-19 vaccination: a comprehensive review of the currently approved vaccines.

Elham Jamshidi, Amirhossein Asgary, Paria Shafiekhani, Yasaman Khajeamiri, Kawthar Mohamed, Hadi Esmaily, Sahand Jamal Rahi, Nahal Mansouri

Open access · goldAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  15. Evaluation of the T cell and B cell response following the administration of COVID-19 vaccines in Korea.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Elham JamshidiFunctional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Amirhossein AsgaryDepartment of Biotechnology, College of Sciences, University of Tehran, Tehran, Iran.
Paria ShafiekhaniUSERN office, Functional Neurosurgery Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Yasaman KhajeamiriSchool of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kawthar MohamedSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Hadi EsmailySchool of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sahand Jamal RahiLaboratory of the Physics of Biological Systems, Institute of Physics, École polytechnique fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Nahal MansouriDivision of Pulmonary Medicine, Department of Medicine, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland.ORCID 0000-0002-8348-0737
Shahid Beheshti University of Medical Sciences · IRÉcole Polytechnique Fédérale de Lausanne · CHTehran University of Medical Sciences · IRUniversal Scientific Education and Research Network · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is unknown how long the immunity following COVID-19 vaccination lasts. The current systematic review provides a perspective on the persistence of various antibodies for available vaccines.Both the BNT162b2 and the mRNA-1273 induce the production of IgA antibodies, reflecting the possible prevention of the asymptomatic spread. The mRNA-1273 vaccine's antibodies were detectable until 6 months, followed by the AZD1222, 3 months, the Ad26.COV2.S and the BNT162b2 vaccines within 2 months.The BNT162b2 produced anti-spike IgGs 11 days after the first dose and peaked at day 21, whereas the AZD1222 induced a neutralizing effect 22 days after the first dose.These vaccines induce T-cell mediated immune responses too. Each one of the AZD1222, Ad26.COV2.S, mRNA-1273 mediates T-cell response immunity at days 14-22, 15, and 43 after the first dose, respectively. Whereas for the BNT162b1 and BNT162b2 vaccines, T-cell immunity is induced 7 days and 12 weeks after the booster dose, respectively.

Indexed as

COVID-19COVID-19 Vaccines2019-nCoV Vaccine mRNA-1273Ad26COVS1Antibodies, NeutralizingAntibodies, ViralBNT162 VaccineChAdOx1 nCoV-19HumansVaccination2019-nCoV Vaccine mRNA-1273Ad26COVS1Antibodies, NeutralizingAntibodies, ViralBNT162 VaccineChAdOx1 nCoV-19COVID-19 VaccinesAntibody persistenceCell-mediated immunityCOVID-19Humoral immunityImmunogenicityLong-term immunityLong-term protectionSARS-CoV-2Vaccines

Identifiers

PMID35417285
PMCPMC9115789
OpenAlexW4223632899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.