Evidence map›Paper›PMID 35417268›Full record

ReviewAmerican journal of physiology. Cell physiology2022

Emerging chemical and biochemical tools for studying 3-

Jian Liu, Lars C Pedersen

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Cell physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Synthetic biology for heparin biomanufacturing.Bioresources and bioprocessing · 2026
    Review
  3. Article
  4. Article
  5. UtilizingAmerican journal of physiology. Cell physiology · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Increased 3-Science advances · 2023
    Article
  11. Review
  12. Review
  13. 3-Computational and structural biotechnology journal · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jian LiuDivision of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina.ORCID 0000-0001-8552-1400
Lars C PedersenGenome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina.
National Institutes of Health · USUniversity of North Carolina at Chapel Hill · US

Funding

Crystallographic studies of macromolecular structuresZICES102645 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PEDERSEN, LARS · 2018 to 2025
$12.6M
Crystallographic studies of macromolecular structuresZIAES102645 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PEDERSEN, LARS · 2009 to 2017
$9.4M
In vitro synthesis of recombinant heparan sulfateR01HL094463 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, JIAN, PAWLINSKI, RAFAL L · 2009 to 2021
$5.2M
Synthesis and Pharmacological Evaluation of Homogenous Ultra-Low Molecular Weight HeparinsR01HL144970 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, JIAN · 2019 to 2021
$946k
Intramural NIH HHS ZIA ES102645NHLBI NIH HHS R01 HL094463NHLBI NIH HHS R01 HL144970
6 · The paper itself

Abstract

Heparan sulfate is a widely expressed polysaccharide in the extracellular matrix and on the cell surface. 3-

Indexed as

SulfatesTandem Mass SpectrometryChromatography, LiquidHeparan SulfateProtein IsoformsSulfotransferasesHeparan SulfateProtein IsoformsSulfatesSulfotransferasesglycosaminoglycansheparan sulfateheparinsulfotransferases

Identifiers

PMID35417268
PMCPMC9169821
OpenAlexW4223547453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.