ReviewAnnual review of nutrition2022
Sex as a Biological Variable in Nutrition Research: From Human Studies to Animal Models.
Review in Annual review of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Beneficial effects of time-restricted fasting on cardiovascular disease risk factors: a meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Effects of castration on growth performance and cecal microbiota in growing raccoon dogs: an exploratory study.BMC veterinary research · 2026Article
- Aging-linked systemic lipid signature is reprogrammed by caloric restriction in rhesus monkeys.Molecular systems biology · 2026Article
- Effects of supplementary protein source, autoclaving diets, and gender on biochemical blood parameters, oxidative stress markers, and caecal fermentation in rats.BMC veterinary research · 2026Article
- Boron Bioavailability Revisited: From Plasma-Accessible Species to Microbiota-Accessible Complexes-Implications for Nutritional Essentiality.Biomolecules · 2025Review
- Adjusting to urban stress: How Eurasian tree sparrows modulate multiple physiological and nutritional markers across sexes.Current zoology · 2025Article
- A researcher's guide to studying sex differences in immune aging.Trends in molecular medicine · 2025Review
- Nutrient-Wide Association Study for Dementia Risks: A Prospective Cohort Study in Middle-Aged and Older Adults.Nutrients · 2025Article
- Animal-derived foods, physical activities, and mild cognitive impairment among Chinese older adults: findings from CLHLS (2008-2018).BMC public health · 2025Article
- Urinary Hippuric Acid as a Sex-Dependent Biomarker for Fruit and Nut Intake Raised from the EAT-Lancet Index and Nuclear Magnetic Resonance Analysis.Metabolites · 2025Article
- Protein diversity, type 2 diabetes, and effect modifiers: a multi-country prospective study.International journal of epidemiology · 2025Article
- Personalized Nutrition in Chronic Kidney Disease.Biomedicines · 2025Review
- Review
- Sex-Based Differences in the In Vitro Digestibility of MCT Emulsions Stabilized by Various Emulsifiers.Foods (Basel, Switzerland) · 2025Article
- Timing of standard chow exposure determines the variability of mouse phenotypic outcomes and gut microbiota profile.Lab animal · 2025Article
- Sex-Specific Factors Associated With Diet Quality in Cancer Survivors: Korea National Health and Nutrition Examination Survey (KNHANES) 2008-2019.Clinical nutrition research · 2025Article
- Global impact of dietary risks on cancers: burdens across regions from 1990 to 2021 and the projection to 2035.Frontiers in nutrition · 2025Article
- Mental health consequences of dietary restriction: increased depressive symptoms in biological men and populations with elevated BMI.BMJ nutrition, prevention & health · 2025Article
- Sex-based difference in immune responses and efficacy of the pneumococcal conjugate vaccine.Journal of leukocyte biology · 2024Article
- Contribution of Sex Differences to the Development of Cardiovascular Disease in Metabolic-Associated Steatotic Liver Disease (MASLD).International journal of translational medicine (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Biological sex is a fundamental source of phenotypic variability across species. Males and females have different nutritional needs and exhibit differences in nutrient digestion and utilization, leading to different health outcomes throughout life. With personalized nutrition gaining popularity in scientific research and clinical practice, it is important to understand the fundamentals of sex differences in nutrition research. Here, we review key studies that investigate sex dimorphism in nutrition research: sex differences in nutrient intake and metabolism, sex-dimorphic response in nutrient-restricted conditions, and sex differences in diet and gut microbiome interactions. Within each area above, factors from sex chromosomes, sex hormones, and sex-specific loci are highlighted.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.