Evidence map›Paper›PMID 35417083›Full record

ArticleAngewandte Chemie (International ed. in English)2022

Dynamic Interconversions of Single Molecules Probed by Recognition Tunneling at Cucurbit[7]uril-Functionalized Supramolecular Junctions.

Bohuai Xiao, Suhang He, Mingjun Sun, Jianghao Zhou, Zhiye Wang, Yunchuan Li, Simin Liu, Werner M Nau, Shuai Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bohuai XiaoThe State Key Laboratory of Refractories and Metallurgy, the Institute of Advanced Materials and Nanotechnology, College of Materials and Metallurgy Wuhan University of Science and Technology, Wuhan, Hubei, 430081, China.
Suhang HeSchool of Science, Jacobs University Bremen, 28759, Bremen, Germany.ORCID 0000-0002-7556-149X
Mingjun SunThe State Key Laboratory of Refractories and Metallurgy, the Institute of Advanced Materials and Nanotechnology, College of Materials and Metallurgy Wuhan University of Science and Technology, Wuhan, Hubei, 430081, China.
Jianghao ZhouThe State Key Laboratory of Refractories and Metallurgy, the Institute of Advanced Materials and Nanotechnology, College of Materials and Metallurgy Wuhan University of Science and Technology, Wuhan, Hubei, 430081, China.
Zhiye WangThe State Key Laboratory of Refractories and Metallurgy, the Institute of Advanced Materials and Nanotechnology, College of Materials and Metallurgy Wuhan University of Science and Technology, Wuhan, Hubei, 430081, China.
Yunchuan LiThe State Key Laboratory of Refractories and Metallurgy, the Institute of Advanced Materials and Nanotechnology, College of Materials and Metallurgy Wuhan University of Science and Technology, Wuhan, Hubei, 430081, China.
Simin LiuThe State Key Laboratory of Refractories and Metallurgy, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan, Hubei, 430081, China.
Werner M NauSchool of Science, Jacobs University Bremen, 28759, Bremen, Germany.ORCID 0000-0002-7654-6232
Shuai ChangThe State Key Laboratory of Refractories and Metallurgy, the Institute of Advanced Materials and Nanotechnology, College of Materials and Metallurgy Wuhan University of Science and Technology, Wuhan, Hubei, 430081, China.ORCID 0000-0001-7405-5555

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We introduce a versatile recognition tunneling technique using doubly cucurbit[7]uril-functionalized electrodes to form supramolecular junctions that capture analytes dynamically by host-guest complexation. This results in characteristic changes in their single-molecule conductance. For structurally related drug molecules (camptothecin, sanguinarine, chelerythrine, and berberine) and mixtures thereof, we observed distinct current switching signals related to their intrinsic conductance properties as well as pH-dependent effects which can be traced back to their different states (protonated versus neutral). The conductance variation of a single molecule with pH shows a sigmoidal distribution, allowing us to extract a pK

Indexed as

Bridged-Ring CompoundsImidazolesCucurbit(n)urilsHeterocyclic Compounds, 2-RingImidazolidinesMacrocyclic CompoundsNanotechnologyBridged-Ring Compoundscucurbit(7)urilCucurbit(n)urilsHeterocyclic Compounds, 2-RingImidazolesImidazolidinesMacrocyclic CompoundsHost-Guest ComplexesMolecular ConductanceMolecular ElectronicsMolecular RecognitionSingle Molecule Spectroscopy

Identifiers

PMID35417083
PMCPMC9324061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.