Evidence map›Paper›PMID 35417030›Full record

ArticleInternational journal of molecular medicine2022

Atorvastatin reduces IOP in ocular hypertension

Xiang-Yuan Song, Ya-Ying Chen, Wen-Ting Liu, Lin Cong, Jin-Ling Zhang, Yang Zhang, Yu-Yan Zhang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Identification of the novel role of sterol regulatory element binding proteins (SREBPs) in mechanotransduction and intraocular pressure regulation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xiang-Yuan SongDepartment of Ophthalmology, Huadong Hospital, Fudan University, Shanghai 200040, P.R. China.
Ya-Ying ChenDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
Wen-Ting LiuDepartment of Ophthalmology, Huadong Hospital, Fudan University, Shanghai 200040, P.R. China.
Lin CongDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
Jin-Ling ZhangDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
Yang ZhangDepartment of Ophthalmology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China.
Yu-Yan ZhangDepartment of Ophthalmology, Huadong Hospital, Fudan University, Shanghai 200040, P.R. China.
Fudan University · CNHuadong Hospital · CNHuashan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the role of atorvastatin in regulating intraocular pressure (IOP) in glaucoma

Indexed as

AtorvastatinGlaucomaMicrofilament ProteinsOcular HypertensionAnimalsCells, CulturedExtracellular MatrixIntraocular PressureMiceTrabecular MeshworkTransforming Growth Factor beta2AtorvastatinFgd4 protein, mouseMicrofilament ProteinsTransforming Growth Factor beta2atorvastatinextracellular matrixFGD4ocular hypertension mouse modelprimary human trabecular meshwork cells

Identifiers

PMID35417030
PMCPMC9015665
OpenAlexW4223537499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.