Evidence map›Paper›PMID 35416899›Full record

ArticleArquivos brasileiros de oftalmologia2021

Measurement of retina/choroid complex perfusion with magnetic resonance imaging in eyes with acute primary angle-closure.

Gabriel Ayub, Brunno M Campos, Thiago J R Rezende, Fernando Cendes, José Paulo Cabral de Vasconcelos, Vital Paulino Costa

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de oftalmologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Bacterial contamination of multi-use antibiotic steroid eye ointments and drops.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gabriel AyubDepartment de Ophthalmology, University of Campinas, Campinas, Brazil.ORCID 0000-0003-2943-2803
Brunno M CamposNeuroimaging Laboratory, University of Campinas, Campinas, Brazil.
Thiago J R RezendeMedical Physics Laboratory, University of Campinas, Campinas, Brazil.
Fernando CendesNeuroimaging Laboratory, University of Campinas, Campinas, Brazil.
José Paulo Cabral de VasconcelosDepartment de Ophthalmology, University of Campinas, Campinas, Brazil.ORCID 0000-0001-8220-6675
Vital Paulino CostaDepartment de Ophthalmology, University of Campinas, Campinas, Brazil.ORCID 0000-0001-6147-4611
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo measure retina/choroid complex perfusion with magnetic resonance imaging in eyes with acute primary angle-closure (APAC).

methodsThree sequences of magnetic resonance imaging, two anatomical and one perfusional using gadolinium, were acquired in patients who were diagnosed with acute primary angle-closure. Regions of interest were drawn on the perfusional sequence and overlaid to the anatomical sequence. The relative blood volume measured during the first 2 s was considered as the baseline value and the change during the subsequent 28 s was analyzed.

resultsFive eyes of 5 patients with acute primary angle-closure were included (3 with unilateral and 2 with bilateral acute primary angle-closure). Three contralateral eyes and 2 eyes of 2 healthy patients, paired for age and sex, were included in the control group. Acute primary angle-closure patients included 4 (80%) women, with an average age of 65.8 ± 12.37 y, mean intraocular pressure of 56.2 ± 14.67 mmHg, mean arterial pressure of 113.4 ± 8.17 mmHg, and average ocular perfusion pressure of 57.2 ± 13.46 mmHg. In the control group, the mean intraocular pressure was 15.6 ± 2.61 mmHg (p=0.0625), the mean arterial pressure was 107.4 ± 6.57 mmHg (p=1.00), and the average ocular perfusion pressure was 91.8 ± 6.72 mmHg (p=0.0625). The relative blood volume of the retina/choroid complex was -0.127 ± 0.048 in acute primary angle-closure patients and -0.213 ± 0.116 in the controls (p=0.3125).

conclusionThe magnetic resonance imaging sequence with gadolinium did not show a change in the retina/choroid complex perfusion in the eyes of patients with acute primary angle-closure.

Indexed as

GadoliniumGlaucoma, Angle-ClosureAcute DiseaseAgedChoroidFemaleHumansIntraocular PressureMagnetic Resonance ImagingMaleMiddle AgedPerfusionRetinaTonometry, OcularGadolinium

Identifiers

PMID35416899
PMCPMC11826561
OpenAlexW3198741171

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.