Evidence map›Paper›PMID 35416876›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2022

Neurobrucellosis: the great mimicker.

Cristiane Nascimento Soares, Abraão Iuri Medeiros Angelim, Carlos Otavio Brandão, Roberto Queiroz Santos, Ravi Mehta, Marcus Tulius Teixeira da Silva

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Isolated oculomotor nerve palsy as the sole presenting feature of neurobrucellosis: a case report.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Brucella brain abscess: a rare but serious neurological complication-case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. mSphere · 2025
    Article
  14. Article
  15. Article
  16. Giant intracranialFrontiers in medicine · 2025
    Article
  17. Neurobrucellosis and Multiple Sclerosis: Cause, Confounder, or Coincidence?Revista da Sociedade Brasileira de Medicina Tropical · 2025
    Article
  18. Doxycycline-Induced Apoptosis inInfection and drug resistance · 2025
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Cristiane Nascimento SoaresHospital Federal dos Servidores do Estado, Departamento de doenças infecciosas, Rio de Janeiro, RJ, Brasil.ORCID http://orcid.org/0000-0001-7678-4006
Abraão Iuri Medeiros AngelimHospital Federal dos Servidores do Estado, Departamento de Neurologia, Rio de Janeiro, RJ, Brasil.ORCID http://orcid.org/0000-0003-2664-9062
Carlos Otavio BrandãoLaboratório Neurolife, Rio de Janeiro, RJ, Brasil.
Roberto Queiroz SantosHospital Federal dos Servidores do Estado, Departamento de Radiologia, Rio de Janeiro, RJ, Brasil.ORCID http://orcid.org/0000-0002-4681-8997
Ravi MehtaImperial College London, Department of Infectious Diseases, London, England.ORCID http://orcid.org/0000-0001-8211-1721
Marcus Tulius Teixeira da SilvaInstituto de Doenças Infecciosas Evandro Chagas, Laboratório de Pesquisa Clínica em Neuroinfecções, Rio de Janeiro, RJ, Brasil.ORCID http://orcid.org/0000-0003-4479-4132
Hospital Federal dos Servidores do Estado · BRInstituto Evandro Chagas · BRNIHR Imperial Biomedical Research Centre · GBUniversidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurobrucellosis is caused by bacteria of the genus Brucella and is responsible for several clinical manifestations, making diagnosis challenging. The most common route of infection is through the consumption of unpasteurized or raw dairy products such as fresh milk, butter, and cheese. As neurological complications can develop chronically, they are frequently misdiagnosed as other infections, such as tuberculosis. This report reviews the clinical manifestations, diagnostic approach, treatment, and prognosis of neurobrucellosis, illustrating a case of chronic intracranial hypertension and meningoencephalitis secondary to brucellosis. The clinical presentation of brucellosis can mimic several systemic diseases, resulting in diagnostic delays and clinical complications. A high degree of suspicion is required, and neurobrucellosis should always be considered in the differential diagnosis of chronic meningitis.

Indexed as

BrucellaBrucellosisMeningoencephalitisNervous System DiseasesDiagnosis, DifferentialHumans

Identifiers

PMID35416876
PMCPMC9009883
OpenAlexW4225647537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.