Evidence map›Paper›PMID 35416769›Full record

ArticleeLife2022

Subash Dhakal, Qiuting Ren, Jiangqu Liu, Bradley Akitake, Izel Tekin, Craig Montell, Youngseok Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Subash Dhakal *Department of Bio and Fermentation Convergence Technology, Kookmin University, Seoul, Republic of Korea.
Qiuting Ren *Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, United States.
Jiangqu Liu *Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, United States.
Bradley AkitakeNeuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, United States.
Izel TekinNeuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, United States.
Craig MontellNeuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, United States.ORCID 0000-0001-5637-1482
Youngseok LeeDepartment of Bio and Fermentation Convergence Technology, Kookmin University, Seoul, Republic of Korea.ORCID 0000-0003-0459-1138
University of California, Santa Barbara · USKookmin University · KRJohns Hopkins University · US

Funding

Molecular Genetics of Taste TransductionR01DC007864 · NIDCD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI CRAIG MONTELL · 2006 to 2026
$7.5M
Opsins as a new class of evolutionarily conserved taste receptors: Diversity Supplement for Pre-Doctoral TrainingR01DC016278 · NIDCD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI CRAIG MONTELL · 2017 to 2026
$4.7M
Opsins and TRP channels controlling sensation and behavior in Aedes aeygptiR01AI165575 · NIAID · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI MONTELL, CRAIG · 2021 to 2025
$2.7M
Mechanisms of visual transduction and light-driven behaviors in Aedes aegyptiR01AI169386 · NIAID · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI CRAIG MONTELL · 2022 to 2026
$2.4M
NIAID NIH HHS R01 AI165575NIAID NIH HHS R01 AI169386NIDCD NIH HHS R01 DC007864NIDCD NIH HHS R01 DC016278
6 · The paper itself

Abstract

The mechanism through which the brain senses the metabolic state, enabling an animal to regulate food consumption, and discriminate between nutritional and non-nutritional foods is a fundamental question. Flies choose the sweeter non-nutritive sugar, L-glucose, over the nutritive D-glucose if they are not starved. However, under starvation conditions, they switch their preference to D-glucose, and this occurs independent of peripheral taste neurons. Here, we found that eliminating the TRPγ channel impairs the ability of starved flies to choose D-glucose. This food selection depends on

Indexed as

Neuroendocrine CellsAnimalsDrosophilaDrosophila melanogasterDrosophila ProteinsFeeding BehaviorFood PreferencesGlucoseSugarsTransient Receptor Potential ChannelsDrosophila ProteinsGlucoseSugarsTransient Receptor Potential ChannelsTRPgamma protein, DrosophilabrainD. melanogasterfeedinginternal statemetabolic sensorneuroendocrine cellsneuroscienceTRP channel

Identifiers

PMID35416769
PMCPMC9068209
OpenAlexW4223648005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.