Evidence map›Paper›PMID 35416543›Full record

ArticleWiener klinische Wochenschrift2022

Symptoms associated with a COVID-19 infection among a non-hospitalized cohort in Vienna.

Nicolas Munsch, Stefanie Gruarin, Jama Nateqi, Thomas Lutz, Michael Binder, Judith H Aberle, Alistair Martin, Bernhard Knapp

Abstract read
In one paragraph

Article in Wiener klinische Wochenschrift, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nicolas MunschScience Department, Symptoma GmbH, Vienna, Austria.
Stefanie GruarinScience Department, Symptoma GmbH, Salzburg, Austria.
Jama NateqiScience Department, Symptoma GmbH, Salzburg, Austria.
Thomas LutzScience Department, Symptoma GmbH, Salzburg, Austria.
Michael BinderVienna Health Care Company, Vienna, Austria.
Judith H AberleCenter for Virology, Medical University of Vienna, Vienna, Austria.
Alistair MartinScience Department, Symptoma GmbH, Vienna, Austria.
Bernhard KnappScience Department, Symptoma GmbH, Vienna, Austria. science@symptoma.com.ORCID http://orcid.org/0000-0002-5714-7105

Funding

Horizon 2020 830017Österreichische Forschungsförderungsgesellschaft 880939
6 · The paper itself

Abstract

backgroundMost clinical studies report the symptoms experienced by those infected with coronavirus disease 2019 (COVID-19) via patients already hospitalized. Here we analyzed the symptoms experienced outside of a hospital setting.

methodsThe Vienna Social Fund (FSW; Vienna, Austria), the Public Health Services of the City of Vienna (MA15) and the private company Symptoma collaborated to implement Vienna's official online COVID-19 symptom checker. Users answered 12 yes/no questions about symptoms to assess their risk for COVID-19. They could also specify their age and sex, and whether they had contact with someone who tested positive for COVID-19. Depending on the assessed risk of COVID-19 positivity, a SARS-CoV‑2 nucleic acid amplification test (NAAT) was performed. In this publication, we analyzed which factors (symptoms, sex or age) are associated with COVID-19 positivity. We also trained a classifier to correctly predict COVID-19 positivity from the collected data.

resultsBetween 2 November 2020 and 18 November 2021, 9133 people experiencing COVID-19-like symptoms were assessed as high risk by the chatbot and were subsequently tested by a NAAT. Symptoms significantly associated with a positive COVID-19 test were malaise, fatigue, headache, cough, fever, dysgeusia and hyposmia. Our classifier could successfully predict COVID-19 positivity with an area under the curve (AUC) of 0.74.

conclusionThis study provides reliable COVID-19 symptom statistics based on the general population verified by NAATs.

Indexed as

COVID-19AustriaCohort StudiesHeadacheHospitalizationHumansSARS-CoV-2ChatbotMachine learningSelf-reportedSymptom assessmentSymptom checker

Identifiers

PMID35416543
PMCPMC9007045

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.